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EC number: 443-870-0 | CAS number: 163520-33-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only summary report available
- GLP compliance:
- no
- Application method:
- contact
- Test organisms (species):
- other: entomology screening species
- Animal group:
- other: arthropods, terrestrial
- Details on test organisms:
- TEST ORGANISMS
Spodoptera littoralis (Egyptian cotton leafworm)
Aphis fabae (Black bean aphid)
Trialeurodes vaporariorum (Greenhouse whitefly)
Nilaparvata lugens (Brown plant hopper)
Oncopeltus fasciatus (Large milkweed bug)
Diabrotica undecimpunctata (Southern corn rootworm)
Tetranychus urticae (Two spotted spider mite)
Blattella germanica (German cockroach)
Musca domestica (Housefly) - Study type:
- laboratory study
- Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 29 Jun - 19 Oct 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EPPO Guideline No. 170 (1992)
- GLP compliance:
- yes
- Application method:
- contact
- Analytical monitoring:
- no
- Vehicle:
- yes
- Details on preparation and application of test substrate:
- - Method of test material application: single topical dose
- Body part: ventral thorax
- Volume of test solution applied: 1.0 μL
- Controls: 1.0 μL acetone
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): acetone - Test organisms (species):
- Apis mellifera
- Animal group:
- Hymenoptera (honeybees)
- Details on test organisms:
- TEST ORGANISM
- Common name: Honey bee
- Source: The bees used for testing were taken from colonies on the land of Hoechst Schering AgrEvo GmbH, Frankfurt am Main, Germany.
- Disease free: yes - Study type:
- laboratory study
- Limit test:
- yes
- Total exposure duration:
- 72 h
- Test temperature:
- 25 - 26 °C
- Humidity:
- 68- 80 %
- Photoperiod and lighting:
- constant darkness during the test period (Observations were made under light.)
- Details on test conditions:
- TEST SYSTEM
- Test container / cage (material, size): wire mesh cages, which were closed at both ends with a cork
Number of test series: 3 ( Control, test - and reference substance)
Number of test concentrations: Test compound: 2; Reference substance: 5
Number of replicates: 5
Number of bees per replicate: 10
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Dead bees were recorded 24, 48 and 72 hours after application of the test or reference substance. - Nominal and measured concentrations:
- 50.4 and 100.7 μg technical substance/bee
- Reference substance (positive control):
- yes
- Remarks:
- Triazophos: 40.9 %w/w
- Duration:
- 72 h
- Dose descriptor:
- LD50
- Effect conc.:
- > 100.7 other: μg technical substance per bee
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: highest test concentration
- Details on results:
- - No mortalities were observed during the test
- No unforeseen circumstances were observed, which may have affected the quality or integrity of this study.
- The study was performed as a limit test, but two concentrations were tested - Results with reference substance (positive control):
- - Results: See "Any other information on results incl. tables", LD50 not reported
- Although the values for the reference substance were slightly above normal they remain within the range of biological variation - Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 02 Sep 1998 - 18 Feb 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: EPPO Guideline No. 170
- GLP compliance:
- yes
- Application method:
- oral
- Details on preparation and application of test substrate:
- - Details of food source: The diet paste was prepared by HMR Deutschland GmbH, ProTox, Analytik, 65795 Hattersheim and consisted of powdered sugar, honey and deionized water.
- Method of feeding during study: through feeding tube - Test organisms (species):
- Apis mellifera
- Animal group:
- Hymenoptera (honeybees)
- Details on test organisms:
- TEST ORGANISM
- Common name: honey bee
- Source: The bees used for testing were taken from colonies on the land of Hoechst Schering AgrEvo GmbH, Frankfurt am Main.
- Disease free: yes - Study type:
- laboratory study
- Limit test:
- no
- Total exposure duration:
- 72 h
- Test temperature:
- 25-26 °C
- Humidity:
- 65-73%
- Photoperiod and lighting:
- Constant darkness during the experimental phase (Observations were made under light.)
- Details on test conditions:
- TEST SYSTEM
- Test container / cage (material, size): Cylindrical test cages of wire mesh screening (12-13 cm high and 5 cm diameter), closed at each end with a cork plug.
- Number of test series: 3 ( Control, test - and reference substance)
- Number of test concentrations: Test compound: 3
- Reference substance: 5
- Number of replicates: 5
- Number of bees per replicate: 10
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Dead and damaged bees were recorded 24, 48 and 72 hours after application.
FOOD CONSUMPTION (if oral study)
- Amount of treated diet consumed per group: see "Any other information on results incl. tables" below - Nominal and measured concentrations:
- Nominal: 0.01; 0.1 and 1% technical substance in diet.
Based on the quantity of food actually consumed during the 5 hr feeding period, the mean
measured dose rates to which the bees were exposed were equivalent to 1.72, 15.04 and
151.96 ug technical substance/bee. - Reference substance (positive control):
- yes
- Remarks:
- Triazophos 40.9% w/w
- Duration:
- 48 h
- Dose descriptor:
- LD50
- Effect conc.:
- > 151.96 µg per animal
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: highest test concentration (1% technical substance)
- Duration:
- 72 h
- Dose descriptor:
- LD50
- Effect conc.:
- > 151.96 µg per animal
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: highest test concentration (1% technical substance)
- Results with reference substance (positive control):
- - Results: see Table 2 under "Any other information on results incl. tables", LD50 not reported
Referenceopen allclose all
Table: Primary screening results: LC 90/100 ppm a.i.
Species |
Treated stage |
AE F122006 WP 20 (ppm a.i.) |
Spodoptera littoralis |
larvae (L4) |
> 1000 |
Aphis fabae |
all stages |
> 1000 |
Trialeurodes vaporariorum |
eggs (3 d) |
> 1000 |
Nilaparvata lugens |
larvae (L3) |
> 1000 |
Oncopeltus fasciatus |
eggs (2 d) |
> 1000 |
Diabrotica undecimpunctata |
larvae (L2) |
> 1000 |
Tetranychus urticae |
all stages |
> 1000 |
Blattella germanica |
larvae (L4) |
> 1000 |
Musca domestica |
adults (1 d) |
> 1000 |
Table 1: Number of dead bees for reference substance
μg product / bee |
Total number of dead bees after: |
||
|
24 h |
48 h |
72 h |
0.1 |
0 |
0 |
0 |
0.2 |
2 |
5 |
5 |
0.3 |
39 |
39 |
39 |
0.4 |
48 |
48 |
48 |
0.5 |
47 |
47 |
47 |
Table 1: Mortality and food consumption with test substance:
% a.i. in diet |
Mean net food consumption per bee (g) |
Ingested dose per bee (μg a.i.) |
Total number of dead bees after: |
||
|
|
|
24 h |
48 h |
72 h |
Control |
0.0164 |
- |
1 |
1 |
3 |
0.01 |
0.0172 |
1.7154 |
0 |
0 |
0 |
0.10 |
0.0150 |
15.0380 |
2 |
2 |
4 |
1.00 |
0.0152 |
151.9600 |
0 |
0 |
1 |
Table 2: Mortality and food consumption with reference substance:
% a.i. in diet |
Mean net food consumption per bee (g) |
Ingested dose per bee (μg a.i.) |
Total number of dead bees after: |
||
|
|
|
24 h |
48 h |
72 h |
Control |
0.0164 |
- |
1 |
1 |
3 |
0.00012 |
0.0284 |
0.03404 |
1 |
2 |
2 |
0.00024 |
0.0238 |
0.05705 |
8 |
8 |
8 |
0.00048 |
0.0212 |
0.10180 |
21 |
21 |
21 |
0.00096 |
0.0190 |
0.18282 |
41 |
42 |
42 |
0.00192 |
0.0215 |
0.41368 |
50 |
50 |
50 |
Description of key information
Key value for chemical safety assessment
Additional information
Two acute studies with honeybees (Apis mellifera) are available according to EPPO Guideline No. 170 (adopted 1992). In the contact toxicity test, two concentrations, 50.4 and 100.7 µg/bee, were applied. In the oral toxicity test, 0.01, 0.1 and 1% of the test substance in the diet was administered. Neither of the tests revealed mortality at the highest concentration investigated. Thus, it is concluded that the LD50 is > 100.7 µg/bee in the contact test and >151.96 µg/bee in the oral toxicity test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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