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EC number: 433-730-7 | CAS number: 23926-51-4 L-THREONINETHYLESTER
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Oxidising properties
Administrative data
Link to relevant study record(s)
- Endpoint:
- oxidising solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2007.08.31 to 2007.11.29
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study performed in accordance with recognized test guidance.
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.17 (Oxidising Properties (Solids))
- GLP compliance:
- yes
- Contact with:
- powdered cellulose
- Sample tested:
- test mixture (not specified)
- Remarks:
- migrated information
- Parameter:
- maximum burning rate
- Result:
- 2.33 other: mm/s (migrated information)
- Remarks on result:
- other: 50% test substance
- Sample tested:
- reference mixture (not specified)
- Remarks:
- migrated information
- Parameter:
- maximum burning rate
- Result:
- 0.68 other: mm/s (migrated information)
- Remarks on result:
- other: 60% reference substance
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The oxidising properties of L-Threonine Ethyl Ester (L-TEE) were evaluated in accordance with EU Method A.17 (Oxidising Properties for Solids). L-TEE was found to be not oxidising.
- Executive summary:
The oxidising properties of L-Threonine Ethyl Ester were evaluated in accordance with EU Method A.17 (Oxidising Properties for Solids).
The burning rates of the test substance mixtures with cellulose were higher than that of the test substance. This suggested that L-TEE may be oxidising and further evaluation was required.
The burning rates in the presence of kieselguhr were higher than those of the equivalent mixtures containing cellulose. This indicates that L-TEE cannot be oxidising because an oxidising material would burn slower in the presence of kieselguhr.
The burning characteristics recorded throughout the test (no vigorous reactions, sooty flame or clean blue flame) are not indicative of oxidation.
The calculated oxygen balance (-168.5%) indicates that L-TEE is within the region where a potential for oxidising properties exists, but there are no potential auxoploses/plosophores present in the chemical structure.
Overall, L-TEE is not considered to be oxidising.
Reference
No vigorus reactions during the tests.
A false positive test was made, where cellulose was substitued by kieselguhr in the train test. Kieselguhr cannot be oxidized and therefore if the burning propagates along trains containing kieselguhr mixture with the test substance, then this is due to entirely burning of the test substance and not to potential oxidative properties. This constitutes a false positive test. This was conducted using mixtures containing between 10 and 90% test substance.
The mixtures of 10, 20, 30 and 40% test substance failed to ignite. The 50% test substance mixture burned with a sooty flame, but only covered a distance of 25 mm. The mixtures of 60, 70 and 80% test substance burned with a sooty flame but not through the whole sample. The burning rate were 4.00, 5.41 and 2.17 mm/sec respectively. The 90% test substance mixture appeared to melt. There were no vigorous reaction during the tests.
Description of key information
The test results indicated that the test material (L-TEE) is not oxidising.
Key value for chemical safety assessment
- Oxidising properties:
- no
Additional information
The oxidising properties of L-TEE were evaluated in accordance with EU Method A.17 (Oxidising Properties for Solids).
The burning rates of the test substance mixtures with cellulose were higher than that of the reference substance. This suggested that L-TEE may be oxidising and further evaluation was required.
The burning rates in the presence of kieselguhr were higher than those of the equivalent mixtures containing cellulose. This indicates that L-TEE cannot be oxidising because an oxidising material would burn slower in the presence of kieselguhr.
The burning characteristics recorded throughout the test (no vigorous reactions, sooty flame or clean blue flame) are not indicative of oxidation.
The calculated oxygen balance (-168.5%) indicates that L-TEE is within the region where a potential for oxidising properties exists, but there are no potential auxoploses/plosophores present in the chemical structure.
Overall, L-TEE is not considered to be oxidising.
Justification for classification or non-classification
Based on these results, L-TEE is not expected to have hazardous properties and is not classified according to GHS and DSD-DPD.
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