Disilver oxide

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

transformation / dissolution of metals and inorganic metal compounds

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media

Deviations:

not specified

Principles of method if other than guideline:

Test were performed at pH 6 and pH 8, with sample loading of 1, 10 and 100 mg/L for a 7 day acute test. A 28 day test was carried out at a sample loading of 1 mg/L at both pHs.

GLP compliance:

not specified

Type of method:

other: Transformation / dissolution

Key result

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

52.51 µg/L

Element analysed:

silver

Loading of aqueous phase:

1 mg/L

Incubation duration:

7 d

Test conditions:

pH 6

Key result

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

62.03 µg/L

Element analysed:

silver

Loading of aqueous phase:

1 mg/L

Incubation duration:

28 d

Test conditions:

pH 6

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

40.51 µg/L

Element analysed:

silver

Loading of aqueous phase:

10 mg/L

Incubation duration:

7 d

Test conditions:

pH 6

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

30 257 µg/L

Element analysed:

silver

Loading of aqueous phase:

100 mg/L

Incubation duration:

7 d

Test conditions:

pH 6

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

19.13 µg/L

Element analysed:

silver

Loading of aqueous phase:

1 mg/L

Incubation duration:

7 d

Test conditions:

pH 8

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

24.8 µg/L

Element analysed:

silver

Loading of aqueous phase:

1 mg/L

Incubation duration:

28 d

Test conditions:

pH 8

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

27.77 µg/L

Element analysed:

silver

Loading of aqueous phase:

10 mg/L

Incubation duration:

7 d

Test conditions:

pH 8

Type of test:

full transformation/dissolution test - metals and sparingly soluble metal compounds

Mean dissolved conc.:

26.04 µg/L

Element analysed:

silver

Loading of aqueous phase:

100 mg/L

Incubation duration:

7 d

Test conditions:

pH 8

Conclusions:

The transformation/dissolution test gave results of 52.51 µg/L after 7 days and 62.03 µg/L after 28 days at a sample loading of 1 mg/L.

Executive summary:

The Transformation/Dissolution of Ag2O was determined following OECD guideline 29 after seven (loading rates of 1, 10 and 100 mg/L) and 28 days (loading rate of 1 mg/L) in OECD media at both pH 6 and pH 8. The transformation/dissolution test gave results of 52.51 µg/L after 7 days and 62.03 µg/L after 28 days at a sample loading of 1 mg/L.

Reference 2

Endpoint:

water solubility

Type of information:

other: Handbook data

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

secondary literature, online database with authoritative values

Qualifier:

no guideline followed

Principles of method if other than guideline:

Not applicable: secondary literature, online database with authoritative values

GLP compliance:

no

Type of method:

other: no data

Water solubility:

ca. 46.4 mg/L

Temp.:

25 °C

Remarks on result:

other: pH not given in reference. Re-calculated to mg/L from original figure of 0.2 mmol/L (molecular mass of Ag2O = 231.74).

Details on results:

no data

Conclusions:

Interpretation of results: slightly soluble (0.1-100 mg/L)
According to the value of 46.4 mg/L (25°C) disilver oxide is slightly soluble in water.

Reference 3

Endpoint:

water solubility

Type of information:

other: Secondary literature

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

secondary literature, online database with authoritative values

Qualifier:

no guideline followed

Principles of method if other than guideline:

Not applicable: secondary literature, online database with authoritative values

GLP compliance:

no

Type of method:

other: no data

Water solubility:

1.6 mg/L

Temp.:

20 °C

Remarks on result:

other: pH not given in reference

Details on results:

no data

Conclusions:

Interpretation of results: slightly soluble (0.1-100 mg/L)
According to the value of 1.6 mg/L (20°C) disilver oxide is slightly soluble in water.

Description of key information

According to reliable secondary literature, disilver oxide is slighly soluble in water (1.6 mg/L at 20°C, Gestis; ca. 46.4 mg/L at 25°C, Holleman-Wiberg). However, water solubility testing is not appropriate for complex metal and sparingly soluble metals and metal compounds. Transformation dissolution testing was therefore conducted for disilver oxide and resulted in a dissolution of 52.51 µg/L after 7 days and 62.03 µg/L after 28 days at a sample loading of 1 mg/L. 

Key value for chemical safety assessment

Water solubility:

62.03 µg/L

at the temperature of:

20 °C

Additional information

The transformation dissolution study by CIMM (2009) reported dissolved disilver oxide concentration of 62.03 µg/L after 28 days at a sample loading of 1 mg/L.