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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06.03.2017 - 16.05.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Analytical monitoring:
yes
Details on sampling:
Analysis of the test media samples was conducted on fresh media at 0 hours and on corresponding old media at 48 hours.
Vehicle:
no
Test organisms (species):
Daphnia magna
Details on test organisms:
Juvenile Daphnia magna (less than 24 hours old) were taken from healthy laboratory cultures maintained in media of the same composition and quality as that used in the toxicity tests. These cultures were setup originally from dormant eggs (ephippia) supplied byMicroBioTests Inc., Belgium.
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Hardness:
280 mg CaCO3/L
Test temperature:
20.2 - 20.6 °C
pH:
7.86 - 8.05
Dissolved oxygen:
96% - 103% ASV
Conductivity:
703 - 780 µS/cm
Nominal and measured concentrations:
6.25, 12.5, 25, 50, 100 mg/L (nominal)
6.08, 12.6, 25.6, 46.3, 108 (measured)
Details on test conditions:
The test was conducted in a temperature and light-controlled facility, with a 16-hour light: 8 hour dark cycle.
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Description of key information

EC50(48 h): > 100 mg/L

Key value for chemical safety assessment

Additional information