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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Testing was conducted between 30 September 2009 and 24 October 2009.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
From GLP certificate in report. Date of inspection: 15 September 2009 Date of Signature: 26 November 2009
Type of method:
effusion method: vapour pressure balance
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa
Transition / decomposition:
no

Results can be seen as an attachment.

Conclusions:
The vapour pressure of the test material has been determined to be 4.5 x 10-15 Pa at 25ºC.
This study is conducted according to an appropriate guideline and under the conditions of GLP and therefore the study is considered to be acceptable and to adequately satisfy both the guideline requirement and the regulatory requirement as a key study for this endpoint.
Executive summary:

The vapour pressure was determined using a vapour pressure balance withasurents being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 Vapour Pressure of CommissionRegulation (EC) No 440/2008 of 30 May 3008.

Summary of results

Run

Log10[Vp(25ºC)]

1

-14.932

2

-14.888

3

-14.043

4

-14.373

5

-14.026

6

-14.447

7

-13.712

Mean

-14.346

Vapour Pressure

4.5 x 10-15Pa

The vapour pressure of the test material has been determined to be 4.5 x 10-15Pa at 25ºC.

Description of key information

One key study exists. This study (Walker J, 2009) was conclusive, done to a valid guideline (EU Method A.4) and the study was conducted under GLP conditions. It is therefore scientifically justified for use as a key study under Regulation (EC) No. 1907/2006.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure was determined using a vapour pressure balance with measurments being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 Vapour Pressure of CommissionRegulation (EC) No 440/2008 of 30 May 3008.

Summary of results

Run

Log10[Vp(25ºC)]

1

-14.932

2

-14.888

3

-14.043

4

-14.373

5

-14.026

6

-14.447

7

-13.712

Mean

-14.346

Vapour Pressure

4.5 x 10-15Pa

The vapour pressure of the test material has been determined to be 4.5 x 10-15Pa at 25ºC.