Registration Dossier
Registration Dossier
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EC number: 220-266-3 | CAS number: 2695-37-6
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16-27 November 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- soil
- Radiolabelling:
- no
- Details on study design: HPLC method:
- Measurement conditions
a) Test equipment
Instrument: High-performance liquid chromatograph
Column: LC-2010CHT (SHIMADZU CORPORATION) Inertsil CN-3 (150 mm x 2.1 mm I.D. particle size 5µm, GL Sciences Inc.)
Column temperature: 25°C
Eluent: Methanol/ buffer (pH 6.5) [pH of 10 mmol/L potassimn dihydrogenphosphate solution was adjusted to pH 6.5 with 0.1mol/Lsodium hydroxide solution] (1/1 v/v)
Flow rate: 0.2mL/min
Measurement wavelength: 210nm
Sample size: 2µL
b) Test temperature
25±1°C - Key result
- Type:
- log Koc
- Value:
- < 1.25
- Temp.:
- 25 °C
- Validity criteria fulfilled:
- yes
- Conclusions:
- The log Koc is <1.25
- Executive summary:
The adsorption coefficient was measured using the HPLC method prescribed by OECD 121 in accordance with GLP. The log Koc was calculated to be <1.25
Reference
Description of key information
The adsorption coefficient was measured using the HPLC method prescribed by OECD 121 in accordance with GLP. The log Koc was calculated to be <1.25
Key value for chemical safety assessment
- Koc at 20 °C:
- 17.78
Additional information
[LogKoc: 1.25]
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