Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Guidance on Safe Use

Guidance on Safe Use

Currently viewing:

Administrative data

First-aid measures

Description of first aid measures:
General advice: Take the victim out of the contaminated area. Remove contaminated clothing immediately and dispose of safely.
If inhaled: Move to fresh air. Make the victim blow his nose. Seek medical advice.
In case of skin contact: Rinse immediately with plenty of water for at least 15 minutes. Seek medical advice.
In case of eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Seek medical advice immediately.
If swallowed: Do not induce vomiting. Make the victim rinse his mouth with water. Seek medical advice.

Most important symptoms and effects, both acute and delayed
Symptoms: Respiratory depression. Drowsiness. Agitation. Anxiety. Hypotensive effect. Shivering. Nausea, vomiting.

Fire-fighting measures

Extinguishing media:
Suitable extinguishing media: All means (e.g. water, carbon dioxide, dry chemical extinguisher).
Unsuitable extinguishing media: Strong water jet.

Special hazards arising from the substance or mixture:
In case of fire, the product may emit toxic and/or irritating fumes. Supposed thermal decomposition/oxidation: Carbon monoxide and carbon dioxide Nitrogen oxides (NOx)

Advice for firefighters:
Special protective equipment: Use self-contained breathing apparatus. Wear full protective suit.
Further information: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Avoid discharging extinguishing water in the environment.

Accidental release measures

Personal precautions, protective equipment and emergency procedures: Particle full face respirator or powered air purifying respirator. Suitable gloves. Dedicated work clothes.

Environmental precautions: Avoid any spreading of the product.

Methods and materials for containment and cleaning up:
General advice: Sweep and shovel the solid product into a container specially adapted for its recovery or destroying (avoiding dust formation). Close and label thoroughly.
Cleaning of contaminated zone: After cleaning up the product, rinse the polluted area with water.
Elimination of recovered materials: Deliver to the Environmental service of the factory or to any specialized and approved disposal company.

Reference to other sections:
Additional advice: Evacuation of area and intervention of special services recommended.

Handling and storage

Precautions for safe handling:
Advice on safe handling (industrial scale): Local ventilation and emission point dust extraction. Enclosed transfer recommended. Take precautionary measures against electrostatic loading. Earth vessels and equipment well.
Advice on safe handling (laboratory scale): Handling in a hood.

Conditions for safe storage, including any incompatibilities:
Requirements for storage rooms and vessels: Keep containers tightly closed in a cool, well-ventilated place.
Advice on common storage: Keep away from chemicals as it is a pharmaceutical substance
Further information on storage conditions: Keep in a well closed container, away from moisture and light.
Storage temperature: Keep away from heat.
Advised packaging material: Glass, polyethylene, polypropylene.
Sensitivity: No particular observation.

Transport information

Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all

Marine transport (UN RTDG/IMDG)

Shippingopen allclose all
Remarksopen allclose all
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Control parameters:
Occupational Exposure Limits: OEL-8h (Sanofi): 35 μg/m3
Remarks: (preliminary)
Sanofi hazard bands-Hygiene: OEB 3 (preliminary)


Personal protection equipment
(IMPORTANT: to be adapted following the workplace risk assessment.)
Industrial workplace
Respiratory protection: Particle full face mask or powered-air purifying respirator.
Hand protection: Suitable gloves. Glove material : Nitrile rubber Layer thickness : 0,11 mm Break through time: > 480 min
Eye/face protection: See respiratory protection.
Body Protection: Dedicated working clothes recommended.
Hygiene measures: Wash hands.

Laboratory
Respiratory protection: Handling in a hood.
Hand protection: Suitable gloves.
Eye/face protection: Safety glasses.
Body Protection:Working clothes.
Hygiene measures: Wash hands.

Stability and reactivity

Safety remarks: Dust may be explosive (no data available).

Reactivity: No data available.
Chemical stability: No data available
Possibility of hazardous reactions: No data available.
Conditions to avoid: No data available.
Incompatible materials: Strong oxidizing agents.
Hazardous decomposition products: Supposed thermal decomposition/oxidation: Carbon monoxide and carbon dioxide Nitrogen oxides (NOx)

Disposal considerations

Waste treatment methods:
Product: Deliver to the Environmental service of the factory or to any specialized and approved disposal service.
Uncleaned packaging: Deliver to the Environmental service of the factory or to any specialized and approved disposal service.