Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-593-1 | CAS number: 143-23-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
No hydrolysis study is required as the substance is ready biodegradable.
The biochemical degradability of the test substance Bis(hexamethylene)triamine at 293 K (20 deg C) was determined according to the OECD Guideline No. 301 D and to EC Method C.4 -E and compliant to GLP (reliability category 1).
Control- and blank-series without test substance were run simultaneously and the effectiveness of the inoculum was confirmed.
For the test substance, the following biodegradability was found:
1 % after 7 days,
49 % after 14 days,
100 % after 17 days,
100 % after 21 dayS,
100 % after 28 days.
Additionally, nitrate measurements in the 28 d samples confirmed a total nitrification of the test substance during the test period.
Therefore the test substance is classified as readily biodegradable according to the guidelines, meeting the 10 days window. Moreover it was found that an inhibitory effect of the test substance on the biochemical degradation of the reference substance at the concentration tested could not be excluded.
The adsorption/desorption behaviour of BHT amine containing the main constituents BHT (64.8%) and HMD (13.8%)
was investigated using four soil types covering a range of different soil properties: Speyer 2.1 (soil I, sand), Speyer 6S (soil II, clay), Empingham (soil III, clay loam), Mechtildshausen (soil IV, loam) and sediment of the River Rhine (soil V, sandy loam). Sorption of BHT to the investigated soils was strong but showed a dependency on the soil involved and on the soil-to-solution ratio used. Sorption was strongest to the clay soil (soil II) and weakest to the sand soil (soil I). With the exception of the river sediment (Soil V), sorption increased with increasing clay content. No correlation of sorption and the soil properties pH value, cation exchange capacity and organic carbon content was observed. The sorbed fraction of analyte increased with the amount of soil used in the batch systems. Apparent equilibrium distribution was reached within 48h. Desorption was investigated for 120h after the 48h adsorption phase. Little desorption was observed and constant solution phase concentrations were reached between 24h and 120h. The adsorption coefficients were calculated after 48h of adsorption, whereas desorption coefficients were calculated after 120h of desorption.
Kd values for BHT were between 201 (soil I) and >51000 (soil II) L/kg (log Kd between 2.3 and >4.7, respectively), for the sediment sample the Kd value was 152 L/kg (log Kd 2.2).
The calculated adsorption and desorption distribution coefficients were independent of the organic carbon content. Therefore, any environmental fate assessment should preferably be based on Kd_ads or Kd_des values.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.