Registration Dossier
Registration Dossier
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EC number: 205-410-5 | CAS number: 140-29-4
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- other information
- Study period:
- No data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: 2.g: Collection of data. Peer-review database
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other: Peer-reviewed database
- Title:
- No information
- Author:
- HSDB
- Year:
- 2 010
- Bibliographic source:
- http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB, CAS n° 140-29-4
Materials and methods
- Principles of method if other than guideline:
- Estimation of BCF using log Kow and a regression-derived equation
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Phenylacetonitrile
- EC Number:
- 205-410-5
- EC Name:
- Phenylacetonitrile
- Cas Number:
- 140-29-4
- Molecular formula:
- C8H7N
- IUPAC Name:
- 2-phenylacetonitrile
- Details on test material:
- No data
Constituent 1
- Radiolabelling:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- no data
Study design
- Route of exposure:
- other: No data
- Test type:
- not specified
- Water / sediment media type:
- not specified
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- 9 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Estimation of BCF using log Kow and a regression-derived equation
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The reported BCF value of 9 is estimated based on the log Kow and a regression-derived equation. Based on this result the substance should not be considered to bioconcentrate in aquatic organisms according to the EC regulation n°1272/2008
- Executive summary:
The authors estimated the bioconcentration factor of phenylacetonitrile (CAS n° 140 -29-4) using the log Kow of the substance and a regression-derived equation. The estimated BCF values of 9 indicates that phenylacetonitrile does not need to be considered to bioconcentrate in aquatic organisms according to the EC regulation n° 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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