Metam-sodium

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

secondary literature

Justification for type of information:

Data is from secondary source

Qualifier:

according to guideline

Guideline:

OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)

Principles of method if other than guideline:

Determination of octanol water partition coefficient of the test substance Metam-sodium.

GLP compliance:

not specified

Type of method:

flask method

Partition coefficient type:

octanol-water

Specific details on test material used for the study:

- Name of test material (IUPAC name): Metam-sodium
- Common name: Sodium methyldithiocarbamate
- Molecular formula: C2H5NNaS2
- Molecular weight: 129.1826 g/mol
- Smiles notation: C(=S)(NC)[S-].[Na+]
- InChl: 1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1
- Substance type: Organic
- Physical state: Solid

Key result

Type:

log Pow

Partition coefficient:

-1.89

Remarks on result:

other: Other details not known

Details on results:

The logKow of test chemical Metam-sodium was determined to be -1.89.

Conclusions:

The partition coefficient (log Pow) value of the substance Metam-sodium was determined to be -1.89.

Executive summary:

The partition coefficient (log Pow) value of the substance Metam-sodium was determined according to OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method). The experimental was carried out using Shake Flask Method. The partition coefficient (log Pow) value of the substance Metam-sodium was determined to be -1.89. Based on the experimental value, chemical Metam-sodium can be considered to be hydrophilic in nature.

Description of key information

Based on the available data from secondary source,the partition coefficient (log Pow) value of the substance Metam-sodium was determined according to OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method) and was evaluated to be -1.89. Based on the experimental value, chemical Metam-sodium can be considered to be hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):

-1.89

Additional information

Based on the available data in a key study from secondary source,the partition coefficient (log Pow) value of the substance Metam-sodium was determined according to OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method) and was evaluated to be -1.89.

In a supportingstudy from authoritative database and secondary source,the partition coefficient (log Pow) value of the substance Metam-sodium was determined to be ranges from -2.04 to -2.05 at a temperature of 22°C and pH 7.0, respectively.

Another supportingstudy from handbook and authoritative databases,the partition coefficient (log Pow) value of the substance Metam-sodium was determined to be <1.0 at a temperature of 25°C, respectively.

In an additional study from secondary source indicates that the partition coefficient (log Pow) value of the substance Metam-sodium was determined to be -2.15 at pH 9.0, respectively.

Thus, on the basis of available information, the logKow value of the chemical Metam-sodium was determined to be ranges from <1.0to -2.05, respectively. On the basis of this value, chemical Metam-sodium can be considered to be hydrophilic in nature.