Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer-reviewed database
Principles of method if other than guideline:
Experimental determination
GLP compliance:
not specified
Dissociating properties:
yes
No.:
#1
pKa:
10.732
Temp.:
25 °C
Remarks on result:
other: Temperature value is an estimate as actual temperature value was not specified
Conclusions:
A pKa value of 10.73 is reported. A pKa of 10.73 indicates dimethylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process
Executive summary:

A pKa value of 10.732 is reported. A pKa of 10.73 indicates dimethylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process.

Description of key information

A pKa value of 10.73 is reported (HSDB, 2010). 

Key value for chemical safety assessment

pKa at 20°C:
10.73

Additional information

A pKa value of 10.73 is reported. This indicates dimethylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process.