Registration Dossier
Registration Dossier
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EC number: 204-407-6 | CAS number: 120-55-8
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
According to the adaptations found in column 2 of annex IX, the bioconcentration in aquatic species study can be waived if direct and indirect exposure to the aquatic environment is unlikely. This substance has no defined uses where direct application to the aquatic environment would occur, and because the substance is readily biodegradable, wastewater treatment would also make indirect exposure to the aquatic environment unlikely. In addition, evidence of a low bioaccumulation potential is provided by QSAR estimates showing BCF values < 100 L/kg using a regression method based upon the experimental log Kow value of 3.2(HLS 1999, VCL 261/972408), and using the Arnot-Gobas QSAR method the BCF/BAF values for all trophic levels are < 10 L/kg when biotransformation rates are utilized and ~ 200 L/kg when biotransformation is not included in the estimation. For these reasons, and for animal welfare reasons, it is believed that a bioconcentration study is not justified and is not proposed.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
