Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-047-7 | CAS number: 102-69-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substance is not readily biodegradable according to OECD criteria, however easiliy eliminated from water after an extended lag phase.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of tripropylamine, (Q)SAR results were additionally used for biodegradation. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Assessment
Biodegradation of tripropylamine (CAS 102-69-2) was assessed in a ready biodegradability test in accordance with OECD Guideline 301 E (Modified OECD Screening Test) with effluent from a laboratory wwtp treating municipal sewage. The test substance concentration was 20 mg/L TOC. After the test period of 28 days no significant biodegradation was observed (DOC removal of 0 - 10 %; BASF AG, 1989, Rep. no. 89/1742).
In a supporting study in accordance with OECD Guideline 302B (Zahn-Wellens Test) tripropylamine was shown to be easily eliminated from water after an extended lag phase. Measured initial test substance concentration was 445 mg/L DOC and the test duration was 41 days. DOC removal until day 21 was 0 %, whereas after 33 days 79 % degradation was observed, and at day 41 tripropylamine was completely eliminated (BASF AG, 1989, Rep. no. 0189/1742).
The biodegradation of tripropylamine was additionally estimated using the QSAR method of CATALOGIC 301C v12.17 (OASIS Catalogic v5.15.2), which predicted an O2-consumption (BOD) of 16 % after 28d (BASF SE, 2022). The substance was completely within the applicability domain of the model.
Based on the available results, tripropylamine is classified as not readily biodegradable according to OECD criteria, however easily eliminated from water after an extended lag phase.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
