Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: 1-chloro-2,3-epoxypropane
  • IUPAC name: 2-(chloromethyl)oxirane
  • Other names
EC / List no.:
203-439-8
CAS no.:
106-89-8
Index number:
603-026-00-6
Molecular formula:
C3H5ClO
SMILES:
ClCC1CO1
InChI:
InChI=1/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2
Type of substance:
Mono constituent substance
Origin:
Organic, Inorganic
Registered compositions:
30
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is toxic if swallowed, is toxic in contact with skin, causes severe skin burns and eye damage, is toxic if inhaled, may cause cancer, is a flammable liquid and vapour and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is harmful to aquatic life with long lasting effects, causes serious eye damage and is suspected of damaging fertility or the unborn child.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is fatal if inhaled.

Breakdown of all 1131 C&L notifications submitted to ECHA

Acute Tox. 3 H301 Harmonised Classification
Acute Tox. 3 H311 Harmonised Classification
Skin Corr. 1B H314 Harmonised Classification
Flam. Liq. 3 H226 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Acute Tox. 3 H331 Harmonised Classification
Aquatic Chronic 3 H412
Eye Dam. 1 H318
Acute Tox. 2 H330
Repr. 2 H361
Skin Sens. 1A H317
Muta. 2 H341
Carc. 1A H350
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
  • Ss

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 82 active registrations under REACH, 2 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

This substance is used in the following products: laboratory chemicals and coating products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: health services and scientific research and development. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, laboratory work, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance and for thermoplastic manufacture. Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following products: paper chemicals and dyes, coating products, washing & cleaning products, water treatment chemicals, cosmetics and personal care products and oil and gas exploration or production products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, laboratory work and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: laboratory chemicals. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, laboratory work and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and in processing aids at industrial sites.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. If exposed or concerned: get medical advice/attention. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a poison center or doctor/physician. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If swallowed: rinse mouth. Do not induce vomiting.

Storage statements

Store this substance locked up; in a well-ventilated place and keeping container tightly closed.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M Wroclaw Sp.z.o.o., ul. Kowalska 143 51-424 Wroclaw Poland
  • AGC Chemicals Europe, Ltd, World Trade Centre Zuidplein 80 1077VX Amsterdam Netherlands
  • AGC Chemicals Europe, Ltd, York House Hillhouse FY5 4QD Thornton Cleveleys Lancs United Kingdom
  • Akzo Nobel Industrial Paints, S. L., Poligono Industrial "Can Prunera" Apartado 9 08759 Vallirana Spain
  • Archroma Distribution and Management Germany GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • Archroma France, SAS, Rue du Flottage 60350 Trosly-Breuil France
  • Archroma Germany GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • Archroma UK, Ltd, Bowling Old Lane BD5 7JL Bradford United Kingdom
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • Baker Hughes Ltd, The Ark, 201 Talgarth Road Hammersmith W6 8BJ London United Kingdom
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Blue Cube Germany Assets GmbH & Co. KG, Buetzflether Sand 2 21683 Stade Germany
  • Blue Cube Netherlands B.V. – OR1, Axelsedam 3a 4531HH Terneuzen Netherlands
  • Cambridge Environmental Assessments part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre Old Naas road D12XV7K Dublin Ireland
  • Caplinq Europe BV, De Trompet 1126 1967 DA Heemskerk - Netherlands
  • Cardolite Specialty Chemicals Europe NV, Wijmenstraat 21 K bus 2 B-9030 Mariakerke (Gent) Belgium
  • CCD (Germany) GmbH, Graf-Adolf-Strasse 68 40210 Düsseldorf Germany
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (Jiangsu Sanmu Group Co., ltd.), Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHS Epi, a.s., Revoluční 1930/6 40032 Ústí nad Labem Czech Republic
  • Clariant Ibérica Producción S.A., Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain
  • Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1 65843 Sulzbach am Taunus Germany
  • Cytec Engineered Materials GmbH in its legal capacity as OR of Cytec Industries Inc., Industriestraße 3 76684 Östringen Germany
  • Dow Belgium B.V.B.A., Sneeuwbeslaan 20, bus 10 2610 Wilrijik Belgium Belgium
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH, Am Kronberger Hang 4 D-65824 Schwalbach Germany
  • Evonik Chemicals Limited, Clayton Lane M11 4SR Clayton Manchester United Kingdom
  • Evonik Chemicals Limited_OR1, Hersham Place Technology Park Molesey Road KT12 4RZ Walton on Thames Surrey United Kingdom
  • Experien Chemical Services (Europe) Limited, 7 Finkle Street YO7 1DA Thirsk United Kingdom
  • GEO SPECIALTY CHEMICALS UK LIMITED, Charleston Road Hardley, Hythe, SO45 3ZG Southampton Hampshire United Kingdom
  • Grace Catalysts & Materials, S.L.U., Carretera N-340, km 1.156 43006 Tarragona Spain
  • Harke Services GmbH-OR3, Xantener Str.1 45479 Mülheim an der Ruhr Germany
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Hexion B.V., Seattleweg 17, building 4 3195 ND Pernis-Rotterdam Netherlands
  • Hitachi Chemical Europe GmbH, Berliner Allee 22 40212 Duesseldorf Germany Germany
  • Huntsman Advanced Materials (Europe) BVBA, Everslaan 45 B-3078 Everberg Belgium
  • Huntsman Advanced Materials (Europe) BVBA OR-C, Everslaan 45 B-3078 Everberg Belgium
  • Huntsman Advanced Materials (Europe) BVBA OR-U, Everslaan 45 B-3078 Everberg Belgium
  • ICC Industries B.V., Arena Boulevard 61, 4th floor 1101 DL Amsterdam Netherlands
  • ICL Europe Coöperatief U.A. (OR1), Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands
  • INEOS Composites Hispania S.L. (0341), Partida Povet, 37 ES-12580 Benicarlo Castillon de la Plana Spain
  • INFO_CARE_USP, Tiberiusweg 9 3453 KZ De Meern Netherlands
  • Innospec Limited (OR1), Innospec Manufacturing Park Oil Sites Road CH65 4EY Ellesmere Port Cheshire United Kingdom
  • INOVYN Deutschland GmbH, Luwigstrasse 12 47495 Rheinberg Germany
  • INOVYN France S.A.S., Avenue de la République 39500 Tavaux France
  • INTERTEK FRANCE, ZAC Ecoparc II 27400 HEUDEBOUVILLE France
  • Isola GmbH, Isolastr 52353 Dueren NRW Germany
  • ITS Testing Services (UK) Ltd 12, Caleb Brett House 734 London Road RM20 3NL West Thurrock, Grays Essex United Kingdom
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • JIANGSU YANGNONG CHEMICAL GROUP CO., LTD.(KONSENS OR), Graf-Adolf-Str. 70 40210 Duesseldorf Germany
  • Kemira Oyj, Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland
  • KIST Europe Forschungsgesellschaft mbH_14, Universitaet des Saarlandes Campus E 71 D-66123 Saarbruecken Germany
  • LORD Germany GMBH, Ottostrasse 28 41836 Hueckelhoven North Rhine - Westphalia Germany
  • Miki Europe GmbH, Immermannstr. 35 40210 Düsseldorf Germany
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • Nalco Europe B.V., Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands
  • NAMA Germany, Teichstrasse 38 D-79539 Lörrach Germany
  • Panasonic Industrial Devices Materials Europe GmbH, Ennshafenstrasse 30 4470 Enns Austria
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. - OR3, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACH24H CONSULTING GROUP (Wuhan Youji Industries Co., Ltd), Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • RHODIA OPERATIONS, 40 rue de la Haie Coq 93306 AUBERVILLIERS France
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
  • SNF SA, ZAC de Milieux 42163 Andrézieux France
  • Solenis Netherlands B.V., Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL Netherlands
  • Sterling Pharma Solutions Ltd, Dudley NE23 7QG Cramlington Northumberland United Kingdom
  • Stewardship Chemicals 27, Green Lowe Farm Shawclough Road, Waterfoot BB4 9SA Rossendale Lancashire United Kingdom
  • StonCor Europe, Rue du Travail, 9 1400 Nivelles Belgium
  • SUEZ Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
  • SUEZ WTS France, Tour CB21 16 Place de l’Iris 92040 Paris La Défense France
  • TÜV SÜD Iberia S.A.U. (052), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • Zeon Europe GmbH, Hansaallee 249 40549 Düsseldorf NRW Germany
  • [Confidential], [Confidential]
  • ADVANCED BIOCHEMICAL EUROPE SPRL, rue de Ransbeek 310 1120 Brussels Belgium
  • Archroma Italy, S.r.l., Via Manzoni 37 20030 Palazzolo Milanese Italy
  • BASF Espanola S.L., Calle Can Ràbia, n. 3-5 8017 Barcelona Spain
  • BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France
  • BASF Italia S.p.A., Via Marconato 8 20811 Cesano Maderno Italy
  • BASF Oy, Tammasaarenkatu 3 00180 Helsinki Finland
  • BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf Germany
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • ENVIGO CRS SAU 156, Centro Industrial Santiga - Carrer Argenters, 6 08130 Santa Perpetua de Mogoda Barcelona Spain
  • Ferro Spain S.A., Carretera Valencia - Barcelona Km 61.5 12550 Almazora (Castellon) Spain
  • Henkel AG & Co. KGaA, Henkelstrasse 67 40191 Duesseldorf North-Rhine Westfalia Germany
  • Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7 2260 Westerlo Belgium
  • Henkel Ireland Operations and Research Limited, Tallaght Business Park Whitestown 24 Dublin Ireland
  • Henkel Ltd., Wood Lane End HP2 4RQ Hemel Hempstead, United Kingdom
  • Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
  • Hexion B.V. OR, Seattleweg 17, Building 4 3195 ND Pernis-Rotterdam Netherlands
  • OQEMA Whyte Limited, Marlborough House 298 Regents Park Road N3 2UA Finchley London United Kingdom
  • Showa Denko Europe GmbH OR1, Konrad-Zuse-Platz 3 D-81829 Munich Germany
  • TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany
  • TÜV SÜD Industrie Service GmbH, Westendstr. 199 80686 München Germany
  • ZACHEM S.A., Wojska Polskiego 65 85-825 Bydgoszcz Poland

Other names

  • -
  • -chloro-2,3-epoxypropane
  • 1-Chlor-2,3-epoxypropan
  • 1-Chloro-2,3-epoxypropane
  • 1-chloro-2,3-epoxypropane; epichlorhydrin
  • 2-(chloromethyl) oxirane
  • 2-(Chloromethyl)oxirane
  • chloromethyloxirane
  • Choromethyloxirane
  • Epichlohydrine
  • Epichlorhydrin
  • EPICHLOROHYDRIN
  • Epichlorohydrin (EPC)
  • Epichlorohydrine
  • Oxirane, 2-(chloromethyl)-
  • 1-chloro-2,3-epoxypropane
  • epichlorhydrin
  • (Chloromethyl)ethylene oxide
  • (Chloromethyl)oxirane
  • .alpha.-Epichlorohydrin
  • .gamma.-Chloropropylene oxide
  • 1,2-Epoxy-3-chloropropane
  • 1-Chloro-2,3-epoxypropane
  • 2,3-Epoxypropyl chloride
  • 2-(Chloromethyl)oxirane
  • 3-Chloro-1,2-epoxypropane
  • 3-Chloro-1,2-propylene oxide
  • 3-Chloropropene-1,2-oxide
  • 3-Chloropropylene oxide
  • Aropol 5-50%
  • CHINT: Epichlorohydrine
  • Chloropropylene oxide
  • Derakane
  • Epichlorhydrin
  • EPICHLOROHYDRIN
  • Epichlorohydrin industrial
  • Epichlorohydryna
  • EPILINK 701
  • Glycerol epichlorohydrin
  • Glycidyl chloride
  • Hetron
  • J 006
  • KAY-4728
  • Mastertop B7
  • Mastertop BC379
  • O0827
  • Oxirane, (chloromethyl)- (9CI)
  • Phase I REACH Kandidat
  • Propane, 1-chloro-2,3-epoxy- (6CI, 8CI)
  • This substance is a monomer in an imported polymer, therefore no trade names are available and/or relevant
  • This substance is a monomer in an imported polymer, therefore no trade names are available and/or relevant.

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Pungent (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 6 studies submitted
  • 2 studies processed
R Melting / freezing point
-57.2 - -57 °C @ 101.325 kPa [3]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-57.1 °C

Boiling point

Study results
  • 3 studies submitted
  • 1 study processed
R Boiling point
117 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
117 °C

Density

Study results
  • 3 studies submitted
  • 1 study processed
R Relative density
1.18 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
1.18

Vapour pressure

Study results
  • 4 studies submitted
  • 1 study processed
R Vapour pressure
22.8 hPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
22.8 hPa @ 25 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
0.45 @ 25 °C and pH 6.8 - 7.1 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
0.45 @ 20 °C

Water solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
65.9 g/L @ 25 °C and pH 6 - 8 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
65.9 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 1 study processed
R Surface tension
72.3 mN/m @ 1.01 g/L and 21.5 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
72.3 mN/m @ 1.01 mg/L

Flash point

Study results
  • 3 studies submitted
  • 1 study processed
R Flash point
40 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
40.05 °C

Auto flammability

Study results
  • 1 study submitted
  • 1 study processed
R Autoflammability / self-ignition
385 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
385.05 °C

Flammability

Study results
  • 2 studies submitted
  • 1 study processed
C Interpretation of results
Flammable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
1.073 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
1.037 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
36 days

Hydrolysis

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 3 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 10.6 µg/L (1)
Intermittent releases (freshwater) 106 µg/L (1)
Marine water 1.06 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 35 mg/L (1)
Sediment (freshwater) 57.2 µg/kg sediment dw (1)
Sediment (marine water) 5.72 µg/kg sediment dw (1)
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 5.22 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 10.6 - 13.2 mg/L [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
10.6 mg/L

Long–term toxicity to fish

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (48 h) 23.9 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
23.9 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 7.1 - 15 mg/L [2]
NOEC (72 h) 1.7 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
15 mg/L
EC10 or NOEC for freshwater algae
1.7 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
35 mg/L

Sediment toxicity

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other 2
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.52 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 1.52 mg/m³ repeated dose toxicity
Local Effects
Long-term: (DNEL) 1.52 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 1.52 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 175 - 282 mg/kg bw (rat) [4]
M/CInterpretations of results
Category 3 based on GHS criteria [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 2 studies submitted
  • 1 study processed
P/RResults
LC50 (60 min) 2 165 - 3 617 ppm (rat) [2]
M/CInterpretations of results
Category 2 based on GHS criteria [1]

inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 250 - 515 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Category 3 based on GHS criteria [1]

dermal
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEL (rat): 1 - 3 mg/kg bw/day [3]
LOAEL (rat): 3 - 7 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant