Registration Dossier
Registration Dossier
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EC number: 232-189-2 | CAS number: 7789-78-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test material
- Reference substance name:
- Calcium dihydroxide
- EC Number:
- 215-137-3
- EC Name:
- Calcium dihydroxide
- Cas Number:
- 1305-62-0
- Molecular formula:
- CaH2O2
- IUPAC Name:
- calcium dihydroxide
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- In the joint chemical report of calcium dihydroxide, three tests studying eye irritation on rabbit and two ran on in vitro (HET-CAM) exist. Two key studies using the OECD guideline N°405 and three supporting study using OECD 405 and the in vitro HET-CAM. In conclusion, the available eye irritation studies (in vivo, rabbit), Ca(OH)2 caused irreversible lesions in the eye.
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