Registration Dossier

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
other:
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1979

Materials and methods

Type of study / information:
Growth inhibition test in the following mammallian cell lines: HeLa, strain R and strain L-132, human fibroblast cell line VA-13 and the rat glial cell line C. Except HeLa cells, the cell lines were obtained from the American Type Cul- ture Association, Parklawn Drive, Rockville, Maryland.

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Cell line

50 % inhibitory concentration (mM)

50 % inhibitory concentration (mg/L)

HeLa

0,063

13,88

Glial

0,081

17,85

WI-38 vtd

0,029

6,39

L-132

0,075

16,53

Applicant's summary and conclusion