Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-881-4
CAS number: 128-37-0
At this high concentration (22
mg/L) the stimulation of the endocrine receptor (ER) was, however, less
than 15 % of the maximum response obtained with 17ß-estradiol. It is
reported that BHT did not “impair binding of tritiated estradiol to the
ER”. Thus, there was no proof for an interaction of BHT with the ER
Jobling et al. used a fish
endocrine receptor (ER) binding assay with Oncorhynchus mykiss cells.
The initial screening process was carried out using a cytosolic extract
from the liver. No stimulation of the receptor activity was determined
for BHT until concentrations exceeded a concentration of 1*10-4
M (22 mg/L). At this high concentration the stimulation of the ER was,
however, less than 15 % of the maximum response obtained with
17ß-estradiol. Jobling et al. additionally reported that BHT did not
“impair binding of tritiated estradiol to the ER”. Thus, there was no
proof for an interaction of BHT with the ER receptor.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Dette websted anvender cookies for at sikre dig den bedste brugeroplevelse.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again