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EC number: 203-825-6
CAS number: 111-01-3
Detail on results :
Pretest body weight (kg)
Terminal body weight (kg)
Time after patch removal
Erythema & Eschar formation
Sum of mean scores
Primary Irritation Index (PII) (=Sum of mean scores/3)
In vivo irritant or corrosive effects of squalan were determined using
EPA OPPTS 870.2500 guideline. The test item was applied on rabbit skin
during 4h. The test sites were scored for dermal irritation at 60min
after removal of wrappings and scored again at 24, 48 and 72h. The
modified Primary Irritating Index is 0.22.
In conclusion, in this study, the squalan is considered non-irritant.
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