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EC number: 203-825-6
CAS number: 111-01-3
The endpoints examined by this predictive software are listed below :
Super endpoints : Carcinogenicity Chromosome damage
Genotoxicity HERG channel inhibition Hepatotoxicity Irritation
Miscellaneous endpoints Mutagenicity Ocular toxicity Rapid
prototypes: bladder disorders Rapid prototypes: blood in urine Rapid
prototypes: bone marrow toxicity Rapid prototypes: bradycardia Rapid
prototypes: chromosome damage in vitro Rapid prototypes:
hepatotoxicity Rapid prototypes: kidney disorders Rapid prototypes:
mitochondrial disfunction Rapid prototypes: nephrotoxicity Rapid
prototypes: splenotoxicity Rapid prototypes: testicular toxicity
Rapid prototypes: thyroid toxicity Reproductive toxicity Respiratory
sensitization Skin sensitization Thyroid toxicity
Miscellaneous endpoints : alpha-2-mu-Globulin nephropathy
Anaphylaxis Bladder urothelial hyperplasia Cardiotoxicity Cerebral
oedema Chloracne Cholinesterase inhibition Chromosome damage in
vitro Cumulative effect on white cell count and immunology
Cyanide-type effects High acute toxicity Methaemoglobinaemia
Nephrotoxicity Neurotoxicity Oestrogenicity Peroxisome
proliferation Phospholipidosis Phototoxicity Pulmonary toxicity
Uncoupler of oxidative phosphorylation
Of these endpoints, no alerts were triggered by the structure of the
The DEREK Nexus system has been designed for the qualitative prediction
of the possible toxicity of chemicals. Of the 45 endpoints examined, no
alerts were triggered by the structure of the substance.
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