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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6,10,15,19,23-hexamethyltetracosane
EC Number:
203-825-6
EC Name:
2,6,10,15,19,23-hexamethyltetracosane
Cas Number:
111-01-3
Molecular formula:
C30H62
IUPAC Name:
2,6,10,15,19,23-hexamethyltetracosane
Test material form:
other: liquid

Study design

HPLC method

Details on study design: HPLC method:
Preparation of sample solution: Test item (0.1106 g) was diluted to 10 mL with tetrahydrofuran.

Preparation of dead time solution: The dead time was determined by measuring the retention time of formamide (purity : 99.94 %, 664 mg/L solution in mobile phase).

As the test item had a high affinity for the stationary phase of the column, the mobile phase was adjusted to 100% tetrahydrofuran after the retention time of DDT in order to elute the highly retained test item.
Testing was carried out at approximately neutral pH with the test item in a non-ionized form.
As the slope of the calibration curve for the reference standards showed good first order correlation and as the retention times between duplicate injections for each solution was consistent, the HPLC method was considered valid for the estimation of adsorption coefficient. Based on the chromatographic data, the test item was considered to be stable during the test procedure.

Results and discussion

Adsorption coefficient
Type:
log Koc
Value:
>= 5.63

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The adsorption coefficient of the test item has been determined to be greater than 4.27 x 105, log10 Koc greater than 5.63. This value indicates that the test item will be environmentally immobile.
Executive summary:

The adsorption coefficient of Squalane (CAS 111-01-3) has been determined to be greater than 4.27 x 105, log10 Koc greater than 5.63, using the HPLC screening method, designed to be compatible with Method C19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001.