Registration Dossier

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1993

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: OECD guideline 402
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
other: New Zealand White Rabbit

Test system

Type of coverage:
occlusive
Vehicle:
other: Test matarial moistened with physical saline
Amount / concentration applied:
2000 mg
Duration of treatment / exposure:
24 h
Number of animals:
10

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
edema score
Basis:
mean
Time point:
24 h
Score:
0
Max. score:
0
Remarks on result:
other: Max. duration: 0d; Max.value at end of observation period:0
Irritation parameter:
erythema score
Time point:
24/48/72 h
Remarks on result:
other: Not available
Irritation parameter:
edema score
Time point:
24/48/72 h
Remarks on result:
other: Not available

Applicant's summary and conclusion