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Diss Factsheets
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EC number: 233-215-5 | CAS number: 10081-67-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Toxicity to terrestrial organisms is discussed.
Additional information
Three higher tier tests are available to assess the toxicity of the substance to terrestrial organisms. The results of these tests are as follows:
OECD Guideline 208 (Terrestrial Plants Test: Seedling Emergence and Seedling Growth Test)
Test soil concentrations of up to 1000 mg/kg resulted in no adverse effects on the seedling emergence and early growth of four of the six species tested (A. sativa, Z. mays, B. napus, G. max).
The NOEC and LOEC for Lactuca sativa (lettuce) were 125 and 250 mg/kg, respectively, based on seedling height.
The NOEC and LOEC for Lycopersicon esculentum (tomato) were 63 and 125 mg/kg, respectively, based on seedling height and dry weight.
OECD Guideline 216 (Soil Microorganisms: Nitrogen Transformation Test)
The EC50 value for inhibition of nitrate formation after 28 days was greater than 2500 mg Naugard 445/kg dry soil, the highest concentration tested. Naugard 445 did not have an adverse effect on nitrogen transformation in soil.
OECD Guideline 222 (Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei))
There was no treatment-related mortality of adult earthworms exposed to 4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline at 62.5, 125, 250, 500, and 1000 mg/kg dry soil for 28 days. Based on body weight and survival data of adult earthworms, the no observed effect concentration (NOEC) was determined to be 1000 mg/kg dry soil, the highest concentration tested. There were no reductions of 50% or greater for the numbers of juveniles produced in the treatment groups in comparison to the negative control group, therefore the EC50 for reproduction was greater than 1000 mg/kg dry soil, the highest concentration tested. The NOEC was 62.5 mg/kg dry soil and the LOEC was 125 mg/kg dry soil, based on the numbers of juveniles produced.
On the basis of these results it is considered that the test substance does not pose a hazard to terrestrial organisms. No further testing is required to refine risk.
.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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