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Diss Factsheets
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EC number: 262-797-3 | CAS number: 61444-38-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (aquatic algae; growth rate)= >1.8mg/L, 72 hour TWA, freshwater, OECD 201, Harlan Laboratories Ltd. 2013
EC10 (aquatic algae; growth rate)= 1.4 mg/L, 72 hour TWA, freshwater, OECD 201, Harlan Laboratories Ltd. 2013
NOEC (aquatic algae; growth rate)= 0.33 mg/L, 72 hour TWA, freshwater, OECD 201, Harlan Laboratories Ltd. 2013
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1.8 mg/L
- EC10 or NOEC for freshwater algae:
- 1.4 mg/L
Additional information
The algal growth inhibition to Pseudokirchneriella subcapitata, was carried out according to OECD 201 Freshwater Alga and Cyanobacteria, Growth Inhibition Test and EU Method C.3 guidelines. Following a preliminary range-finding test, P.subcapitata was exposed to solutions of the test item at nominal concentrations of 1.0, 3.2, 10, 32 and 100 % (v/v) saturated solution (three replicate flasks per concentration) for 72 hours, under constant illumination and shaking at a temperature of 24 ± 1 °C. Analysis of the test preparations at 0 hours showed measured concentrations to range from 0.0042 to 5.5 mg/L. Given that the test item was known to be unstable under test conditions, it was considered appropriate to provide samples for analysis at 24, 48 and 72 hours in order to better define the rate in decline in measured concentration. Analysis of the test preparations at 24 hours showed concentrations in the range of 0.0049 to 3.6 mg/L were obtained. At 48 hours concentrations in the range of less than the limit of quantification (LOQ), determined to be 0.0046 mg/L, to 0.042 mg/L were obtained whilst a further decline in measured concentration to less than the LOQ in all test samples was observed at 72 hours. Given this decline in measured test concentration, in accordance with Guideline requirements it was considered appropriate to calculate the results based on the time-weighted mean measured test concentrations only. The 72h-NOEC for growth rate reduction based on TWA concentrations was 0.33 mg/l. The 72h-EC50 for growth rate reduction (72h-ERC50) based on TWA concentrations was >1.8 mg/l. The study met the acceptability criteria prescribed by the guideline.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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