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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- other: Expert Assessment
- Remarks:
- Expert Assessment
- Adequacy of study:
- key study
- Study period:
- 07 October 2021
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Cinnamidopropyl trimethyl ammonium chloride has been assessed for the self-ignition temperature endpoint. The assessment is based on the physical properties of the substance.
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- An assessment was performed based on the examination of the physical properties of the test substance Cinnamidopropyl trimethyl ammonium chloride.
- GLP compliance:
- no
- Key result
- Remarks on result:
- other: Based on the expert assessment conducted on the test substance Cinnamidopropyl trimethyl ammonium chloride, an interaction between the substance and air in which the substance would self-heat is highly unlikely.
- Conclusions:
- The flashpoint of the liquid was determined to be >200 °C and thus auto-flammability is not a relevant property of this substance and the endpoint can be waived for the purpose of REACH based on column 2 of Annex VII.
- Executive summary:
Cinnamidopropyl trimethyl ammonium chloride has been assessed for the self-ignition temperature endpoint. The assessment is based on the physical properties of the substance.
Cinnamidopropyl trimethyl ammonium chloride is observed to be a deliquescent substance. According to IUPAC this means that the vapour pressure of the saturated aqueous solution of the substance is less than the vapour pressure of water in the air. When the water vapour is collected by the pure solid compound, a mixture of the solid and liquid or an aqueous solution of the compound forms until the substance is dissolved and is in equilibrium with its environment. Self-ignition temperature measures the ability of solid substance to react with air and, without an energy supply, self-heat. As Cinnamidopropyl trimethyl ammonium chloride is deliquescent it absorbs waterfrom the air and dissolves. This means that an interaction between the substance and air in which the substance would self-heat is highly unlikely.
The solid substance readily absorbs water and, during various experimental studies, the substance was noted to be a viscous liquid, therefore auto- flammability may be a more relevant endpoint. However, according to column 2 of Annex VII of REACH; the study does not need to be conducted for liquids that are not flammable in air, e.g no flashpoint up to 200 °C. The flashpoint of the liquid was determined to be >200 °C for Cinnamidopropyl trimethyl ammonium chloride and therefore the auto-flammability is not a property of concern for this substance.The flashpoint of the liquid was determined to be >200 °C and thus auto- flammability is not a relevant property of this substance and the endpoint can be waived for the purpose of REACH based on column 2 of Annex VII.
Reference
Endpoint Assessment Report
Self-Ignition Temperature
Introduction
Cinnamidopropyl trimethyl ammonium chloride (IUPAC: 1-propanaminium, N,N,N-trimethyl-3-(1-oxo-3-phenyl-2-propenyl)amino-, chloride) has been assessed for the self-ignition temperature endpoint. The assessment is based on the physical properties of the substance.
Assessment: Self-Ignition Temperature
Cinnamidopropyl trimethyl ammonium chloride is observed to be a deliquescent substance. According to IUPAC this means that the vapour pressure of the saturated aqueous solution of the substance is less than the vapour pressure of water in the air. When the water vapour is collected by the pure solid compound, a mixture of the solid and liquid or an aqueous solution of the compound forms until the substance is dissolved and is in equilibrium with its environment (IUPAC Gold Book). Self-ignition temperature measures the ability of solid substance to react with air and, without an energy supply, self-heat. As Cinnamidopropyl trimethyl ammonium chloride is deliquescent it absorbs water from the air and dissolves. This means that an interaction between the substance and air in which the substance would self-heat is highly unlikely.
The solid substance readily absorbs water and, during various experimental studies, the substance was noted to be a viscous liquid, therefore auto- flammability may be a more relevant endpoint. However, according to column 2 of Annex VII of REACH; the study does not need to be conducted for liquids that are not flammable in air, e.g no flashpoint up to 200 °C. The flashpoint of the liquid was determined to be >200 °C for Cinnamidopropyl trimethyl ammonium chloride and therefore the auto-flammability is not a property of concern for this substance.
Conclusion
Cinnamidopropyl trimethyl ammonium chloride is observed to be a deliquescent substance. The solid substance readily absorbs water and as a result the interaction between the substance and air in which the substance would self-heat is highly unlikely. The substance is noted to be a viscous liquid and therefore auto-flammability was considered as a more relevant endpoint compared to self- ignition. The flashpoint of the liquid was determined to be >200 °C and thus auto-flammability is not a relevant property of this substance and the endpoint can be waived for the purpose of REACH based on column 2 of Annex VII.
IUPAC Gold book – Definition of deliquescent https://goldbook.iupac.org/terms/view/D01582 accessed 10th August 2021
Description of key information
The flashpoint of the liquid was determined to be >200 °C and thus auto-flammability is not a relevant property of this substance and the endpoint can be waived for the purpose of REACH based on column 2 of Annex VII.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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