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Diss Factsheets
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EC number: 947-979-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10-12 September
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Good quality study under GLP with certificate of analysis, however no chemical analyses. Therefore all concentrations in this report are nominal.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- no chemical analyses
- Principles of method if other than guideline:
- no chemical analyses
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
no - Analytical monitoring:
- no
- Details on sampling:
- no chemical analyses
- Details on test solutions:
- Direct dispersion in water. 1.0 g of test material was dispersed in 1 litre of diluent to give a stock solution of 1.0 g/l. 200 ml of this stock solution
was dispersed in 2 litres of diluent to give a 100 mg/l stock solution from which serial dilutions were made to give the test series. The test material
was suspected to absorb to glassware and so saturation of the absorption sites was achieved by soaking the test vessels overnight prior to the
start of the test with the test solutions. At 0 hours the test vessels were emptied, rinsed with the solution to fresh test solution.
tested concnetrations: 1.0, 1.8, 3.2, 5.6, 10, 18, 32, 56 and 100 mg/l. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia Magna Straus
Source: Laboratory culture originating from a strain supplied by the Institut National de Recherche Chimique Appliquée (I.R.CH.A), France
Culture: At 21 ºC in polypropylene vessels containing two litres of dechlorinated and aged tap-water. Cultures were fed daily with a suspension of
mixed algea (predominantly Chlorella spp.). Culture conditions ensure that reproduction is by parthenogenesis.
Selection: Gravid adults were isolated 24 hours prior to initiation of the test. Young daphnids produced overnight were used for testing. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- no
- Hardness:
- approximately 50 mg/L as CaCO3
- Test temperature:
- 22ºC
- pH:
- 7.3-7.4
- Dissolved oxygen:
- 8.3-8.4 mg O2/L
- Salinity:
- no data
- Nominal and measured concentrations:
- nominal concentrations: 1.0, 1.8, 3.2, 5.6, 10, 18, 32, 56 and 100 mg/l.
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95%CL (6.4-10 mg/L)
- Results with reference substance (positive control):
- no reference substance tested
- Reported statistics and error estimates:
- 48 h EC50= 8 mg/L with 95% Condifence Limits of 6.4-10 mg/L
- Validity criteria fulfilled:
- yes
- Conclusions:
- Good quality study, however no chemical analyses therefore all concentrations nominal.
- Executive summary:
Study Sponsor: Berol Nobel Nacka AB
Project Number: 116/95
Test Substance: Ampholak XO7
Test Spscies: Daphnia magna (Straus) tested in the 1st instar.
Test Type: Acute toxicity. 48 h EC50 (immobilisation).
Test Conditions: Static test conditions according to OECD Guideline No. 202, Part 1 referenced as Method C.2 of Commission Directive 84/449/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
Results
24 h EC50 = 62 mg/L (17 mg ai/l) 95 % confidence limits: 51 - 76 mg/L (15- 19 mg ai/l)
48 h EC50 = 8.0 mg/L (2.4 mg ai/l) 95 % confidence limits: 6.4 - 10 mg/L (1.9 - 3.0 mg ai/l)
ai= active ingredient
"No Observed Effect Concnetration" (NOEC) at 24 h = 32 mg/l ( 9.6 mg ai/l)
"No Observed Effect Concnetration" (NOEC) at 48 h = 3.2 mg/l ( 1.0 mg ai/l)
Reference
Concentration (mg/L) |
Cumulative immobilized Daphnia (initial population : 10 per concentration) |
|||||||
24 hours |
48 hours |
|||||||
R1 |
R2 |
Total |
% |
R1 |
R2 |
Total |
% |
|
Control |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1.0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1.8 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
3.2 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
5.6 |
0 |
0 |
0 |
0 |
5 |
4 |
9 |
45 |
10 |
0 |
0 |
0 |
0 |
8 |
8 |
16 |
80 |
18 |
0 |
0 |
0 |
0 |
9 |
8 |
17 |
85 |
32 |
0 |
0 |
0 |
0 |
9 |
9 |
18 |
90 |
56 |
4 |
6 |
10 |
50 |
9 |
9 |
18 |
90 |
100 |
7 |
8 |
15 |
75 |
10 |
10 |
20 |
100 |
Description of key information
One acute daphnia study with Sodium oleylamphopolycarboxy glycinate is available. The study lacks the quantification of the test substance during the test. The study from Handley and Wetton (1992) resulted in a 48h EC50 for daphnia magna of 2.4 mg a.i./L based on nominal test concentrations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.4 mg/L
Additional information
One acute daphnia study with Sodium oleylamphopolycarboxy glycinate is available. The study lacks similar to the two fish studies the quantification of the test substance during the test. When these studies were performed no suitable sensitive analytical method was available for the quantification of this test substance. The study from Handley and Wetton (1992) resulted in a 48h EC50 for daphnia magna of 2.4 mg a.i./L based on nominal test concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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