Registration Dossier
Registration Dossier
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EC number: 695-735-2 | CAS number: 68489-14-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Reason / purpose for cross-reference:
- reference to same study
Reference
Description of key information
According to the ECHA Guidance document R7b, no further test on the toxicity to microorganisms has to be conducted if the toxicity control in a ready biodegradability test shows no inhibitory effects on microorganisms. As the toxicity control in the OECD 301F Biodegradability test showed no inhibition of the microbial activity at a substance concentration of 100 mg/L, no further test is necessary to evaluate the respiration inhibition of activated sludge. The concentration used in the toxicity control (100 mg/L) can be used as NOEC value.
Key value for chemical safety assessment
Additional information
A biodegradation test was carried out following the methods outline in the OECD 301F guidelines. The toxicity control vessel, containing the test item and aniline, achieved 37% biodegradation after 14 days and 41% biodegradation after 28 days. This confirms the test item is not toxic to the sewage treatment micro-organisms used in the test. The test concentration of the substance was 100mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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