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EC number: 606-826-3 | CAS number: 217308-07-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000-12-14 - 2000-12-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study according to OECD guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Benzeneacetic acid, .alpha.-hydroxy-, monoammonium salt, (.alpha.R)-
- EC Number:
- 606-826-3
- Cas Number:
- 217308-07-1
- Molecular formula:
- C8 H8 O3 .H3 N
- IUPAC Name:
- Benzeneacetic acid, .alpha.-hydroxy-, monoammonium salt, (.alpha.R)-
- Test material form:
- other: liquid
- Details on test material:
- - Name of test material (as cited in study report): (R)-Ammoniummandelat solution (ca. 30 %), purity
- Physical state: liquid, light yellowish, Iight turbid
- Analytical purity: 29.1-31.2 % Ammoniummandelat, 70 % water
- Lot/batch No.: 30193/89
- Expiration date of the lot/batch: no limitation of storage
- Storage condition of test material: storage at the refrigerator (4-10°C)
- Water-solubility: miscible in any relation
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Municipal activated sludge from laboratory wastewater treatment plant fed with municipal sewage and synthetic wastewater.
- Concentration of sludge: 30 mg/l - Duration of test (contact time):
- 14 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Initial conc.:
- 118 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Test temperature: 22 +- 2°C
- pH: 7.4-7,8
TEST SYSTEM
- Number of culture flasks/concentration: 2
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: yes
SAMPLING
- Sampling frequency: on days 0, 1, 3, 5, 7, 10, 13, 14
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2
- Abiotic sterile control: 1
- Toxicity control: 1
- Inhibition control: 1
- Adsorption control: 1
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (DOC removal)
- Value:
- 90 - 100
- Sampling time:
- 14 d
- Details on results:
DOC (mg/l, average values):
time BC RS IH PC AC TS
(d)
0 0.9 20.6 40.9 22.1 22.5 22.5
1 0.3 20.4 40.2 21.9 21.9 21.7
3 1.1 17.8 17.3 21.5 22.7 1.4
5 0.7 1.5 2.4 21.2 22.0 1.7
7 1.0 1.7 2.6 20.9 1.8
10 0.9 1.3 2.0 21.8 1.0
13 1.2 1.5 1.7 21.9 1.4
14 0.9 1.3 2.0 23.5 1.0
DOC decrease (%):
time RS IH PC AC TS
(d)
0 0 0 0 0 0
1 1 0 1 0 1
3 15 60 3 0 99
5 96 96 4 1 95
7 96 96 5 97
10 98 97 1 99
13 98 99 1 99
14 97 97 -6 99
BC = blank control
RS = reference substance
IH = inhibition control
PC = abiotic control
AC = adsorption control
TS = test substance
- test duration: 14 days
- adaptation phase: 1 day
- degradation phase: 2 days
- elimination of test substance by adsorption: 0-10 % after 5 days
- 10-day window met: yes
Kinetic of test substance (in %):
1 after 1 day(s)
99 after 3 day(s)
99 after 14 day(s)
Kinetic of control substance (in %):
15 after 3 day(s)
96 after 5 day(s)
BOD5 / COD results
- Results with reference substance:
- 90-100 (% DOC) after 14 days
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
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