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EC number: 600-872-8 | CAS number: 108419-35-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 November 1985 to 20 November 1985 and 02 December 1985 to 04 December 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 985
- Report date:
- 1985
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Acetic acid, C11-14-isoalkyl esters, C13-rich
- EC Number:
- 283-740-9
- EC Name:
- Acetic acid, C11-14-isoalkyl esters, C13-rich
- Cas Number:
- 84712-50-5
- Molecular formula:
- C15H30O2
- IUPAC Name:
- Acetic acid, C11-14-isoalkyl esters, C13-rich
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: A colorless liquid, Batch I
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- - Sampling method: Samples were taken from all test concentrations (pooled replicates) on Day 0, before adding test organisms and at termination. BW2 for test material preparation and
stock solutions were also sampled during the study. All samples were collected in duplicate.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: The water soluble fraction of MRD-84-521 was prepared by combining approximately 16.75 ml of the test material with 2.5 liters of BW2 in a carboy. The mixture was then stirred for approximately 72 hours on a stirring platform. After the mixing period, the 100% WSF was drawn off through a sampling tube for use as the stock solution.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: Cultured in environmental laboratory
- Age of parental stock (mean and range, SD): Trial 2 from 15 day old parents
Trial 3 from 13 day old parents
- Feeding during test: Not fed
ACCLIMATION
- Acclimation period: Acclimation by rearing
- Type and amount of food: Cultures of Daphnia were fed Selenastrum capricornutum and a trout chow mixture. Algae were cultured in the Aquatic Laboratory using modified ASM-1 media.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 156 to 166 mg/L
- Test temperature:
- Trial 2- 20.73 +/- 0.54°C
Trial 3 20.92 +/- 0.41°C - pH:
- 8.1 to 8.5
- Dissolved oxygen:
- 8.3 to 9.5 mg/L
- Nominal and measured concentrations:
- Nominal: 0, 6.25, 12.5, 25, 50, 100 % WSF
- Details on test conditions:
- TEST SYSTEM
- Test vessel: The test chambers were 400 ml glass chambers containing a volume of 250 ml of test solution.
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
- Biomass loading rate: Loading during the study did not exceed 40 daphnids per liter of test solution.
OTHER TEST CONDITIONS
- Photoperiod: 16 hours light, 8 hours dark
- Light intensity: Trial 2- Range 74 to 80 footcandles, Trial 3- Range 78-85 footcandles
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : immobilization
RANGE-FINDING STUDY
Based on previous study 252142
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 other: % WAF
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (dissolved fraction)
- Basis for effect:
- mobility
- Details on results:
- There was insufficient mortality in Trial 2 to calculate an LC50 value. There was no mortality in Trial 3. No calculations were performed and no statistical analysis is presented.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Based on the estimated 48-h LC50 of >100% (WAF), the test material is not classified as acutely toxic to freshwater algae according to Regulation (EC) No. 1272/2008 (CLP).
- Executive summary:
There was insufficient mortality in Trial 2 to calculate an LC50 value. There was no mortality in Trial 3. No calculations were performed and no statistical analysis is presented. Therefore a 48 -h LC50 of >100% (WAF) is considered.
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