Registration Dossier
Registration Dossier
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EC number: 266-023-5 | CAS number: 65996-88-5 The distillate from coke oven light oil having an approximate distillation range below 100°C (212°F). Composed primarily of C4 to C6 aliphatic hydrocarbons.
Carcinogenicity
Administrative data
Description of key information
The substance benzol forerunnings (coal) contains > 0.1% Benzene and can also contain > 0.1% 1,3 -butadiene. Benzene and 1,3 -butadiene are known carcinogens.
Long term carcinogenicity studies on benzene have confirmed that benzene is a carcinogen producing different types of tumours in animals (including lymphomas and leukemia). Epidimiologiocal studies on Benzene also found evidence for a causal relationship between benzene exposure and leukaemia. Due to the significant presence of benzene in benzol forerunnings (coal) the substance as a whole also has to be considered as a carcinogen.
1,3-butadiene has produced several type of tumors in animal studies. In addition epidimiological research has consistently found that exposure to 1,3-butadiene can result in increased cancer occurence. Therefore any substance containing >0.1% 1,3-butadiene has to be considered as a carcinogen.
Key value for chemical safety assessment
Justification for classification or non-classification
CAS 65996 -88 -5 has a harmonised classification as H350 (carc. 1B).
The carcinogenicity classification is in addition also supported by the presence of benzene and 1,3 butadiene, known cat 1A carcinogens in quantities in excess of 0.1%. Both of those substances also have a harmonised classification as carcinogen.
Additional information
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