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EC number: 249-854-8 | CAS number: 29797-40-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- deviations from the current OECD-guideline were not reported, but validity criteria may be assessed only partially
- Justification for type of information:
- GLP-study, deviations from the current OECD-guideline were not reported, but validity criteria may be assessed only partially
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- not specified
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Not applicable
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): laboratory sewage treatment plant, conducted with domestic effluent
- Initial cell/biomass concentration: 0.03 g dry weight /L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- not specified
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Details not provided
- Reference substance:
- aniline
- Preliminary study:
- Details not provided
- Test performance:
- Details not provided
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- Please refer to table presented in the field "Overall remarks"
- Results with reference substance:
- The reference substance degraded to 94% within the test period of 28 days.
- Validity criteria fulfilled:
- yes
- Remarks:
- Oxygen consumption of inoculum blank < 60 g/L; others were not reported
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- 0% degradation odf dichloromethylbenzene was observed within 28 days.
- Executive summary:
A 28-d Manometric Respirometry Test was performed with dichloromethylbenzene mixture according to the OECD Guideline 301F. Test substance concentration was 100 mg/L.
0% degradation was observed within 28 days.
Dichloromethylbenzene mixture is not readily biodegradable.
Reference: Caspers & Müller, 1991
Reference
Theoretical oxygen demand: 1590 mg O2/g.
Results
Time [d] |
O2-consumption test substance [mg/L] |
O2-consumption Inoculum blank [mg/L] |
Degradation rate
[%] |
2 |
3 |
3 |
0 |
4 |
- |
- |
- |
6 |
4 |
6 |
0 |
8 |
- |
- |
- |
10 |
5 |
7 |
0 |
12 |
- |
- |
- |
14 |
5 |
7 |
0 |
16 |
5 |
7 |
0 |
18 |
- |
- |
- |
20 |
5 |
7 |
0 |
22 |
5 |
7 |
0 |
24 |
5 |
7 |
0 |
26 |
- |
- |
- |
28 |
5 |
7 |
0 |
Description of key information
The ready biodegradability of dichloromethylbenzene mixture was tested in a 28-d Manometric Respirometry Test according to the OECD Guideline 301F. 0% degradation was observed within 28 days.
Dichloromethylbenzene mixture is not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Key study
A 28-d Manometric Respirometry Test was performed with dichloromethylbenzene mixture according to the OECD Guideline 301F. Test substance concentration was 100 mg/L. 0% degradation was observed within 28 days.
Dichloromethylbenzene mixture is not readily biodegradable.
Reference: Caspers & Müller, 1991
Supporting study
A 28-d Modified MITI Test was performed with 2,4-dichlorotoluene according to the OECD Guideline 301C. Test substance concentration was 100 mg/L. 0% degradation was observed within 28 days.
2,4-dichlorotoluene is not readily biodegradable.
Reference: MITI, 1993
Further studies
A 28-d Closed Bottle Test was performed with 3,4-dichlorotoluene according to the OECD Guideline 301D. Test substance concentration was 4.17 mg/L. 0% degradation was observed within 28 days.
3,4-dichlorotoluene is not readily biodegradable.
As only a short abstract is available, the reliability cannot be assessed.
Reference: NITE database, 2002
A 30-d Manometric Respirometry Test was performed with a dichlorotoluene mixture containing more 2,6-dichlorotoluene according to the EU Guideline C.5.2 and to GLP. Test substance concentration was 100 mg/L. 0% degradation was observed within 30 days.
The tested dichlorotoluene mixture is not readily biodegradable.
As only a short abstract is available, the reliability cannot be assessed.
Reference: FhG, 1989
A 20-d Closed bottle test was performed with another similar dichloromethylbenzene mixture. Test substance concentrations were 2.4, 8, 24 and 80 mg/L.
0 % biodegradation was observed.
As only a a short abstract is available, the reliability cannot be assessed.
Reference: Bayer, 1983
A 20-d biodegradation test (not further specified) was performed with the isomer 2,4-dichlorotoluene. Test substance concentrations were 2.4 - 80 mg/L. 0% degradation was observed. Reliability 3 due to the use of adapted sludge.
Reference: Verschueren, >= 1996
An incomplete entry in IUCLID4 on a BOD5 -determination with a mixture of 2,6- 2,4- and 2,5 -dichlorotoluene (containing more 2,6-dichlorotoluene compared with the mixture, which is described in this dossier): ThOD = 1590 mg/g. Results for BOD5 and COD are not reported.
Reliability 3 due to missing results.
Reference FhG, 1989
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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