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Diss Factsheets
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EC number: 234-514-3 | CAS number: 12007-60-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- other: theoretical statement
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Theoretical statement based on literature data.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Details on sampling:
- Not applicable
- Buffers:
- Not applicable
- Estimation method (if used):
- Not applicable
- Details on test conditions:
- Not applicable
- Number of replicates:
- Not applicable
- Preliminary study:
- Not applicable
- Test performance:
- Not applicable
- Transformation products:
- not measured
- Key result
- Remarks on result:
- not measured/tested
- Remarks:
- Based on existing information sourced from the scientific and regulatory literature it is concluded that hydrolysis testing is not necessary for dilithium tetraborate. These substances are expected to form boric acid if exposed to water or moist soils in the environment. Boric acid is extremely stable and is not susceptible to hydrolysis in environmental media.
- Details on results:
- There are many boron substances (e.g. borate salts, boron halides) that release boric acid as a result of relevant transformation pathways (e.g. hydrolytic, oxidative, digestive or metabolic) at environmentally or physiologically relevant conditions (i.e., pH and concentration); which are considered to be precursors of boric acid.
In the Environment and Climate Change Canada (ECCC) Health Canada Draft Screening Assessment of Boric acid, its Salts and its Precursors it was concluded that several lithium and calcium borates are precursors of boric acid (ECCC, 2016; ECCC, 2014).
In the Inventory Multi-Tiered Assessment and Prioritisation (IMAP) Environmental Tier II Assessment for Boric Acid and Precursors to Boric Acid performed by the Australian National Industrial Chemicals Notification and Assessment Scheme (NICNAS), it was concluded that several sodium salts of boric acid are expected to dissociate and/or hydrolyse to release boric acid at neutral pH (NICNAS, 2017). It is reasonable to draw the same conclusion to lithium borate in terms of its expected dissociation/transformation to boric acid in contact with water.
Boric acid, [B(OH)3], is a very weak, monobasic acid that acts as a Lewis acid by accepting a hydroxyl ion to form the borate anion, [B(OH)4]-. At higher concentrations and pH levels greater than 9.2, the borate anion [B(OH)4]- becomes predominant.
B(OH)3 + 2H2O¿[B(OH)4]- + H3O+
Therefore, at the near neutral pH of most environmental systems and at low concentrations (<0.025 mol B/L), the neutral mononuclear species (B(OH)3) will dominate and only a small proportion of boron will exist as the borate monoanion, B(OH)4- (WHO, 1998).
In the Transitional Annex XV dossier for Boric Acid (Boric acid crude natural) submitted by Austria, the following statement is provided for the hydrolysis endpoint: “Boric acid is an inorganic compound and does not have any chemical bonds prone to hydrolysis. Hydrolysis is therefore not a relevant degradation pathway for boric acid under environmentally relevant conditions”. Therefore, once dilithium tetraborate has transformed to boric acid in water, no further hydrolysis is anticipated.
Based on existing information sourced from the scientific and regulatory literature it is concluded that hydrolysis testing is not necessary for dilithium tetraborate. These substances are expected to form boric acid if exposed to water or moist soils in the environment. Boric acid is extremely stable and is not susceptible to hydrolysis in environmental media.
References
Environment and Climate Change Canada (2016). Draft Screening Assessment Boric Acid, its Salts and its Precursors. Available via: http://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=2A581398-1#toc0822
Environment Canada and Health Canada. 2014. Supporting documentation: Scoping Document for Boron-containing substances. Gatineau (QC): Environment Canada. Information in support of the Draft Screening Assessment for Boric acid, its salts and its precursors.
NICNAS 2017. Environment Tier II Assessment for Boric Acid and Precursors to Boric Acid. Available via:
https://www.nicnas.gov.au/chemical-information/imap-assessments/imap-assessments/tier-ii-environment-assessments/boric-acid-and-precursors
WHO (1998). Environmental health criteria 204–Boron. Geneva. Available via: http://www.inchem.org/documents/ehc/ehc/ehc204.htm. - Validity criteria fulfilled:
- not applicable
- Conclusions:
- Based on existing information sourced from the scientific and regulatory literature it is concluded that hydrolysis testing is not necessary for dilithium tetraborate. These substances are expected to form boric acid if exposed to water or moist soils in the environment. Boric acid is extremely stable and is not susceptible to hydrolysis in environmental media. No futher testing is therefore required.
- Executive summary:
A theoretical statement was produced in order to satisfy the Annex VIII (Tonnage =10 t/y) REACH requirements relating to hydrolysis testing as a function of pH. The hydrolysis test is designed to provide information on abiotic degradation that can help in classification, persistence testing and in determining the fate of a substance in environmental surface waters.
The hydrolysis testing requirement under EU REACH may be waived only if the substance is readily biodegradable or the substance is highly insoluble in water. However, the test item does not meet either of these waivers. However, based on existing information sourced from the scientific and regulatory literature it is concluded that hydrolysis testing is not necessary for dilithium tetraborate. These substances are expected to form boric acid if exposed to water or moist soils in the environment. Boric acid is extremely stable and is not susceptible to hydrolysis in environmental media. No futher testing is therefore required.
Reference
Description of key information
Based on existing information sourced from the scientific and regulatory literature it is concluded that hydrolysis testing is not necessary for dilithium tetraborate. These substances are expected to form boric acid if exposed to water or moist soils in the environment. Boric acid is extremely stable and is not susceptible to hydrolysis in environmental media. No further testing is therefore required.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.