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Diss Factsheets
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EC number: 221-516-4 | CAS number: 3129-92-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 November 2002 to 29 November 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- 1992
- Deviations:
- not specified
- GLP compliance:
- yes
- Specific details on test material used for the study:
- The test substance is cyclohexylamine benzoate. The test substance was obtained from the study Sponsor on 5th September 2002 and stored in the original container at 15 ± 2°C.
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: Scophthalmus maximus (Marine turbot).
- Details on test organisms:
- The test organisms were juvenile Scophthalmus maximus (turbot). The organisms were obtained from a supplier, France Turbot, L‛ Epine France on 2 October 2002. The fish were free of malformations and in good health prior to the definitive test.
- Test type:
- semi-static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- not reported
- Test temperature:
- The temperature of the test medium was 13.5 -15.0°C.
- pH:
- The pH values throughout the test were 7.23 – 8.77.
- Dissolved oxygen:
- The dissolved oxygen was 81.1 % - 98.9% air saturation values.
- Salinity:
- The salinity was 33.5 - 35.2 parts per thousand.
- Nominal and measured concentrations:
- The study was conducted with nominal test concentrations of 100.0, 177.8, 316.2, 562.3, and 1000.0 mg/L.
- Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- All animals in the control vessels survived the 96-hour test period. After 96 hours exposure to concentrations of the test substance, the LC50 value was determined to be >1000.0 mg/L. The 24-h, 48-h and 72-h values were also determined to be >1000.0 mg/L.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Exposure of Scophthalmus maximus to a series of test concentrations showed no mortality. The 96-h LC50 and the 96-h NOEC were each reported as 1000 mg/L.
Reference
Description of key information
The key study was a semi-static acute toxicity test on the effects of the substance on the marine turbot fish, Scophthalmus maximus following OECD guideline 203. Exposure of Scophthalmus maximus to a series of test concentrations showed no mortality. The 96-h LC50 and 96 -h NOEC were each reported as > 1000 mg/L. .
Key value for chemical safety assessment
Marine water fish
Marine water fish
- Effect concentration:
- 1 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.