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Diss Factsheets
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EC number: 206-637-2 | CAS number: 360-64-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- o-(trifluoromethyl)benzamide
- EC Number:
- 206-637-2
- EC Name:
- o-(trifluoromethyl)benzamide
- Cas Number:
- 360-64-5
- Molecular formula:
- C8H6F3NO
- IUPAC Name:
- 2-(trifluoromethyl)benzamide
- Test material form:
- solid: crystalline
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Activated sludge from the municipal wastewater treatment plant Breisgauer Bucht was used as inoculum with a concentration corresponding to 30 mg dry solids per litre. The treatment plant clarifies predominantly domestic wastewater of the region of Freiburg and has a capacity of 600.000 inhabitant equivalents. Sampling date of activated sludge was 9 August 2016. Dry solid of the activated sludge was determined as 3.4 g/L by weight measurements after 2.0 h drying at 105°C (mean of triplicate measurements). The activated sludge was washed twice with tap water by settling the sludge, decanting the supernatant and re-suspending the sludge.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 54 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4.7
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- The reference compound sodium acetate reached the pass level for ready biodegradability (60% ThOD and 10-day window) within 8 days. The pH in the test bottles at the end of the test was 8.8 - 9.0.
Any other information on results incl. tables
Test item:
The biodegradation of the test item was 4.7% within 28 days (mean value of three
replicates, see table 2). Therefore the criterion for ready biodegradability was not met (60%
ThOD and 10-day window).
The pH in the test bottles at the end of the test was 7.6.
Toxicity control:
The degradation in the toxicity control reached 26.7% within 8 days (see table 2) and was thus above the criterion for inhibition effects to the inoculum (<25% on day 14). The test item had no toxic effect to the inoculum according to the validity criteria of OECD 301. The pH in the vessel was 8.6.
Blank:
The oxygen consumption of the blanks was 18.7 mg O2/L in 28 days (mean of three replicates, see table 1). The pH in the vessels was 7.6.
Temperature:
The temperature range was 20.1 - 21.6 °C throughout the whole study.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The biodegradation of the test item was 4.7% within 28 days (mean value of three replicates, see table 2). Therefore the criterion for ready biodegradability was not met (60% ThOD and 10-day window).
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