Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-977-3 | CAS number: 112-49-2
Endpoint summary
Administrative data
Description of key information
There is one reliable study available on the skin irritancy potential Triethylene glycol dimethyl ether was tested for its skin irritant properties in 6 Albino-Russian rabbits. The study was performed according to OECD Guideline 404. Deviation was a prolonged exposure period (24 hours). These conditions make the study design more rigid compared to the regarding OECD Guideline. No effects on skin occurred.
There is one reliable study available on the eye irritancy potential. Triethylene glycol dimethyl ether was tested for its eye irritant properties in 3 rabbits. The study was performed equivalent to OECD Guideline 405. A slight transient effect was found, which were fully reversible. Triethylene glycol dimethyl ether is not irritating to eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
The skin irritation of triethylene glycol dimethyl ether was investigated according to OECD 404. No irritating effect was found. No classification is warranted.
The eye irritation of triethylene glycol dimethyl ether was investigated according to OECD 405. A slight transient effect was found, which were fully reversible. No classification is warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
