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Diss Factsheets
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EC number: 203-600-2 | CAS number: 108-62-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 2007 - January 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- - Name: META Metaldehyde techn.
- Molecular weight: 176.2 g/mol
- Expiration date: 10-Jul-2009
- Analysis date: 11-Jul-2006
- Appearance: white powder
- Storage conditions:4 to 8°C - Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- Prior to use samples of activated sludge from the municipal sewage plant at Taunusstein-Bieidenstadt dealing with predominantly domestic sewages was washed
twice with mineral nutrient solution of the "Manometric-Respirometry-Test" to eliminate organic components and carbonates from the sludge. After resolution with mineral nutrient medium the sludge was homogenised in a "Waring Blender" at low speed for 2 minutes and then filtered through a cotton filter previously carefully rinsed with deionised water. The filtrate was used as inoculum (10 ml/L corresponding to 1% of the final volume of the test solution) on the same day of preparation. The dry matter content of that inoculum was 21.7 mg/L (corresponding to 0.2 mg/L in the final test solution). - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- standard test design following OECD 301F
- Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- no pretest performed
- Test performance:
- The study was conducted with the test item, reference substance and toxicity control
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 2.8
- Sampling time:
- 28 d
- Details on results:
- Based on the results of a toxicity control (containing both the test item and a reference item) the test item can be considered as not inhibitory towards microorganisms at the concentration tested. Regarding the results obtained within this study the test item may be considered "not readily biodegradable". The reference item sodium benzoate was degraded 91% within 28d. The threshold of >= 60% was met within 4.5d (71.5%) of incubation.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- After 28d, a mean degradation value of 2.8% of the test item was measured. Regarding the results obtained within this study the test item may be considered "not readily biodegradable".
- Executive summary:
The test item was tested for biodegradability using the Manometric Respirometry test method according to OECD Guideline 301 F. The degradation process was followed by the oxygen uptake in the test solutions. After 28d a mean degradation
value of 2.8% of the test item was measured. Based on the results of a toxicity control (containing both the test item and a reference item) the test item can be considered as not inhibitory towards microorganisms at the concentration tested.
Regarding the results obtained within this study the test item may be considered "not readily biodegradable". The reference item sodium benzoate was degraded 91% within 28d. The threshold of >= 60% was met within 4.5d (71.5%) of incubation.
pH-values measured within all test solutions at times t0d and t28d were all in the required range of 6-8.5.
Reference
Description of key information
The test item was tested for biodegradability using the Manometric Respirometry test method according to OECD Guideline 301 F. After 28d a mean degradation value of 2.8% of the test item was measured. Regarding the results obtained within this study the test item may be considered "not readily biodegradable". The reference item sodium benzoate was degraded 91% within 28d.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Source: GLP-report
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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