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EC number: 866-700-0 | CAS number: 2102522-55-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 8 May 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Version / remarks:
- 22 January 2001
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
- Specific details on test material used for the study:
- - Storage conditions: The test material was stored in a dark storage place at room temperature.
- Radiolabelling:
- no
- Test temperature:
- 25 °C
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: High performance liquid chromatograph (No. LC-134). LC-2010 AHT (Built in ultraviolet and visible spectrophotometer) (Shimadzu) (measurement wavelength 210 nm for reference item and 258 nm for test material).
- Type, material and dimension of analytical (guard) column: Inertsil CN-3 (150 mm x 2.1 mm I.D., particle size 5 μm, GL Sciences).
MOBILE PHASES
- Type: Methanol/purified water (60/40 v/v)
- Flow rate: 0.2 mL/min
REFERENCE SUBSTANCE
- Formamide (201.1 mg, 1 mL; 10 mL Methanol),
- N, N-Dimethylbenzamide (11.0 mg, 1 mL; 10 mL Methanol)
- Atrazine (10.1 mg, 1 mL; 10 mL Methanol)
- Linuron (2.12 mg, 1 mL; 2 mL Methanol)
- 1, 2, 3, - Trichlorobenzene (10.1 mg, 0.5 mL; 10 mL Methanol)
- Phenanthrene (10.2 mg, 2 mL; 10 mL Methanol)
- DDT (11.1 mg, 2 mL; 10 mL Methanol).
DETERMINATION OF RETENTION TIMES
- Quantity of test substance introduced in the column: 2 μL
- Quantity of reference substances: 2 μL
- Intervals of calibration: The reference material solution was injected before and after the injection of the test material solution to confirm that the retention times of the reference material did not change. Order was: reference material solution (first time), test material solution (first time), test material solution (second time), solvent blank, reference material solution (second time).
REPETITIONS
- Number of determinations: The test material retention time was measured twice.
EVALUATION
- Calculation of capacity factors k: Calculated from the retention time of the test material, using the following equation:
k = (tR - t0) / t0
Where:
tR: Retention time of reference material (min)
t0: Dead time (min) (average of two measured values).
- Determination of the log Koc value: The adsorption coefficient of the test material was calculated using the regression equation of regression line and was given as the average value of two calculated values.
log Koc = a x log k + b
Where:
a: Slope of regression equation
b: Intercept of regression equation - Key result
- Sample No.:
- #1
- Type:
- log Koc
- Value:
- 4.16 dimensionless
- Temp.:
- 25 °C
- Remarks on result:
- other: pH not reported
- Details on results (HPLC method):
- log Koc of the test material was 4.16. It was judged that the test results were valid because the difference between two measured values was less than 0.25.
- Transformation products:
- not measured
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the conditions of this study the log Koc of the test material was determined to be 4.16.
- Executive summary:
The adsorption coefficient on soil and on sewage sludge of the test material was investigated in accordance with the standardised guidelines OECD 121 under GLP conditions, following the HPLC Method.
The study was carried out using an HPLC system. The mobile phase was HPLC Methanol/purified water (60/40 v/v). The reference substances used to create the calibration curve were Formamide, N, N- Dimethylbenzamide, Atrazine, Linuron, 1,2,3- Trichlorobenzene, Phenanthrene and DDT.
Under the conditions of this study the log Koc of the test material was determined to be 4.16.
Reference
Description of key information
The log Koc of the test material was determined to be 4.16.
Key value for chemical safety assessment
- Koc at 20 °C:
- 14 454.4
Additional information
The adsorption coefficient on soil and on sewage sludge of the test material was investigated using the HPLC method in accordance with the standardised guidelines OECD 121 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
The study was carried out using an HPLC system. The mobile phase was HPLC Methanol/purified water (60/40 v/v). The reference substances used to create the calibration curve were Formamide, N, N- Dimethylbenzamide, Atrazine, Linuron, 1,2,3- Trichlorobenzene, Phenanthrene and DDT.
Under the conditions of this study the log Koc of the test material was determined to be 4.16.
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