Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
11 March 2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable method for pigments with low solubilities

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Principles of method if other than guideline:
Calculation of log Pow from the solubility in octanol (see section 4.9) and the solubility in water (see section 4.8 ).
Type of method:
other: calculation
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
other: The analytical methods for the underlying data are given in section 4.8 and 4.9

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
2 158
Temp.:
25 °C
pH:
7.2
Type:
log Pow
Partition coefficient:
3.3
Temp.:
25 °C
pH:
7.2
Details on results:
See below

Any other information on results incl. tables

At ambient temperature (24 -25°C, 25°C given here), the solubility in octanol was determined to be 4100 µg/L (section 4.9) and the solubility in water was determined to be 1.9 µg/L (section 4.8). The pH value given is the mean from 3 determinations in the water solubility study.

With the equation given above, the follwoing values were calculated:

Pow = 4100 µg/L / 1.9 µg/L

Pow = 2158

log Pow = 3.3

Applicant's summary and conclusion

Conclusions:
The test substance has a log Pow of 3.3.
Executive summary:

The log Pow of the test substance was calculated from the solubilities in water and in octanol. The log Pow at 25 °C was 3.3.