Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1982
Report date:
1982

Materials and methods

Principles of method if other than guideline:
no guideline specified
GLP compliance:
not specified
Test type:
other: not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
''amyl nitrite'', mixed isomers
EC Number:
203-770-8
EC Name:
''amyl nitrite'', mixed isomers
Cas Number:
463-04-7
Molecular formula:
C5H11NO2
IUPAC Name:
pentyl nitrite
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
505 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
other: Category 4 based on EU GHS criteria
Conclusions:
The LD50 of the test item in the rat was determined to be 505 mg/kg bw.
Executive summary:

In an report published by Federation Proceedings, Federation of American Societies for Experimental Biology and cited in RTECS, the test item revealed an oral LD50 in the rat of 505 mg/kg bw.