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EC number: 246-186-9
CAS number: 24347-58-8
Octanol/water partition coefficient test of 2,3-butanediol((2R,3R)-rich)
was performed by the shake flask method following the OECD Test No.107
(Adopted 27.07.95) and in compliance with GLP.
Prior to the partition coefficient test, the validation for the
analytical method was performed, showing recoveries of
2,3-butanediol((2R,3R)-rich) in both phases (n-octanol and water phase)
were of 96.4±2.1 and 96.7±2.8%, respectively. The log Pow values of
2,3-butanediol((2R,3R)-rich) from the three duplicate runs with three
different solvent ratios were -0.71±0.01, -0.76±0.02 and -0.70±0.00,
respectively. Therefore, the average value of log Pow for
2,3-butanediol((2R,3R)-rich) was determined to be -0.72±0.03. It was
within the acceptable range (less than ±0.3 units) specified by OECD
Log Pow for 2,3-butanediol((2R,3R)-rich) was determined to be -0.72±0.03.
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