Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Three studies are used for the derivation of an acute toxicity reference value (Parametrix 2005a; Parametrix 2005b; Schubauer-Berigan et al.,1993) at pH 6 and 8. These studies have demonstrated that nickel toxicity increases with pH; therefore, acute toxicity values for pH ca. 8.0 are used for derivation of the toxicity reference value. The testing conditions (pH 8.3 – 8.7 and hardness of 258 – 290 mg/L as CaCo3) in these studies were sufficiently similar to allow for statistical analysis of the results. The geometric mean of 6 LC50 values was 0.068 mg Ni/L or 68 µg Ni/L (see table below).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
68 µg/L

Additional information

Acute Toxicity Data for Ceriodaphnia dubia Used for Deriving the Acute Toxicity Reference Value

Reference

Substance Tested

pH

Hardness (mg/L as CaCO3)

LC50 (48 hr) (mg Ni/L)

Schubauer-Berigan et al., 1993

NiCl2

8.7

290

0.013

Parametrix, 2005a

NiCl2

8.3

258

0.074

 

NiCl2

8.4

266

0.088

Parametrix, 2005b

NiCl2

8.4

280

0.082

 

NiCl2

8.7

290

0.13

 

NiCl2

8.5

290

0.11

LC50 Geometric Mean under similar testing conditions

0.068