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EC number: 203-444-5
CAS number: 106-93-4
Sárvári, 2010a, was selected as the key information for this endpoint as it was conducted according to the OECD 111 guideline with a supporting preliminary study and was the most recent study available. Based upon the study guideline, date of the study report and depth of reporting the study was awarded the reliability score of 1 according to the criteria of Klimisch et al, 1997.Although the registered substance was found to be almost stable at pH 7, hydrolysis was observed at pH 4 and 9 and hydrolysis rate was directly related to a rise in temperature.Half-lives were reported between 141 hours at 67 ºC and 9136 hours at 25 ºC for test solutions at pH 4, and between 114 hours at 67 ºC and 20546 hours at 25 ºC for test solutions at pH 9.
The key information for hydrolysis is taken
from the definitive study of Sárvári, 2010a, which reported
(pseudo-)first order half-lives in water as follows:
These definitive results were based upon the
findings of the preliminary study (Sárvári, 2010b) which reported the
need for the definitive study and the following results:
A large amount of supporting information is
available for this endpoint. The results of these additional studies are
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