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EC number: 200-680-0
CAS number: 68-19-9
Following repeated oral administration for 7 days cyanocobalamin alone
exerted a slight antinociceptive effect at 5620 mg/kg bw p.o.
The number of writhing reactions was reduced by 18% compared to the
In the present acute oral toxicity study, the maximum tolerated dose was
determined for cyanocobalamin. The test substance was given alone or in
combination at a ratio of 1:1:0.0025 for thiamine, pyridoxine, and
cyanocobalamin, to female mice. No toxic effects were observed for the
test substance given alone or in combination up to a dose level of 5000
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