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EC number: 500-155-9 | CAS number: 62362-49-6 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1 October 2018 to 14 March 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Remarks:
- Additional water solubility information is available in the Algal Growth Inhibition Test.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Specific details on test material used for the study:
- Purity: 100% (UVCB)
Appearance/Physical state: Solid, white pastille
Storage: Room temperature in the dark - Key result
- Water solubility:
- >= 0.015 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- ca. 4.3 - ca. 4.4
- Conclusions:
- In a study conducted according to OECD 105, using the shake flask method, the water solubility has been determined to be less than or equal to
1.45 E-2 g/L of solution at 20.0 +/- 0.5 deg.C. - Executive summary:
The water solubility of the test item was detemined to be less than or equal to 1.45 E-2 g/L of solution at 20.0 +/- 0.5 deg. C, using the flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008, and OECD Guidelines for Testing of Chemicals No. 105, 27 July 1995.
In an algal growth inhibition test, the substance concentration in the test samples collected at 0, 24, 48 and 72 hours was determined by high performance liquid chromatography with mass spectrometry (HPLC-MS) using an external standard. Quantitation was based on a single peak attributed to the major component of the test item. Analysis of the test preparations at 0 hours showed that measured test concentrations ranged from 0.0022 to 0.67 mg/L. At 72 hours, measured concentrations ranged from less than the Limit of Quantification (LOQ, 0.000516 mg/L) to 0.0095 mg/L.
Reference
As the test item is a UVCB, the shake flask method was performed.
The three definitive test samples gave widely varied results. There was also no trend across the three samples with respect to test item contact time with the purified water. Therefore, the highest concentration result has been used as a limit value for the water solubility endpoint.
As the test item was confirmed to be surface-active in the surface tension test and all three cleaned-up solutions indicated a distinct Tyndall beam, it is possible that the test results were due to emulsification as opposed to actual solubility.
As such, it was considered that further testing was unnecessary in this instance.
Description of key information
In a study conducted according to OECD 105, using the shake flask method, the water solubility has been determined to be less than or equal to 1.45 E-2 g/L of solution at 20.0 +/- 0.5 deg.C.
Key value for chemical safety assessment
Additional information
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