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EC number: 486-070-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 26 SEP 2007 to 23 JAN 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 25 200 mg/L
- Temp.:
- 20 °C
- pH:
- 4.5
- Details on results:
- The measured results differ by less than 15%. Therefore, the study is considered to be valid.
- Conclusions:
- The water solubility of DIMETHYL 2-METHYL GLUTARATE at 20 °C was determined to be 25.2 g/L (standard deviation ± 0.2 g/L) using the flask shaking method.
- Executive summary:
The determination of the water solubility of DIMETHYL 2-METHYL was performed according to the EEC Directive 92/69, A.6 ”Water Solubility” (1992) and the OECD guideline No. 105, ”Water Solubility” (1995) using the flask shaking method.
The saturation concentration of DIMETHYL 2-METHYL GLUTARATE at room temperature was estimated by a simplified flask method in the preliminary test to be higher than 10-2g/L. Therefore, the flask shaking test was used for the performance of the main test.
Vessels containing water and test item were shaken for 24 hours, 48 hours and 72 hours, respectively, at 30 °C. Afterwards the samples were equilibrated for another 24 hours at 20.0 °C. After dilution with acetonitrile the concentrations in the aqueous solutions were determined by a GC-method.
The water solubility of DIMETHYL 2-METHYL GLUTARATE at 20 °C was determined to be 25.2 g/L (standard deviation ± 0.2 g/L) using the flask shaking method.
Reference
Table 2: Results of the Water Solubility of DIMETHYL 2-METHYL GLUTARATE
Sample N°. |
Shaking time at 30°C |
Concentration analyzed (mg/L) |
Concentration calculated (g/L) |
Water solubility calculated (rounded) (g/L) |
1 2 |
72 |
49.989 50.887 |
24.99 25.44 |
25.20 SD = 0.19 |
3 4 |
48 |
50.172 50.480 |
25.09 25.24 |
|
5 6 |
24 |
50.764 50.065 |
25.38 25.03 |
The saturation mass concentration is calculated from the bold values.
SD = standard deviation
Description of key information
The water solubility of DIMETHYL 2-METHYL GLUTARATE at 20 °C was determined to be 25.2 g/L (standard deviation ± 0.2 g/L) using the flask shaking method.
Key value for chemical safety assessment
- Water solubility:
- 25.2 g/L
- at the temperature of:
- 20 °C
Additional information
One experimental study, scored as Klimisch 1, is available (Weissenfeld M., 2008) and selected as a key study.
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