Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 258-420-7 | CAS number: 53185-52-7
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 11 October 2006 to 30 October 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Version / remarks:
- 1981
- GLP compliance:
- no
- Dissociating properties:
- no
- Conclusions:
- The substance has no dissociating properties.
- Executive summary:
Both the titration method and the conductometric method according to OECD TG 112 study were performed. Based on the results of both methods, it was concluded that the substance has no dissociating properties. The substance has no dissociation constant (pKa value).
Reference
Titration method: There was no difference between the titration curve of the test solution and of blank solution (purified water) either with titration solution of 0.1 M HCl or with 0.1 M NaOH. No inflection point was detected.
Conductometric method: The average electrical conductivity was 3.65µS/cm for the 1000 mg/L test solution. Lower values (1.06 - 1.59 µS/cm) were obtained for the lower test concentrations.
Description of key information
No dissociating properties (OECD TG 112: titration method and conductometric method). The substance has no dissociation constant (pKa value).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
