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Diss Factsheets
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EC number: 219-323-5 | CAS number: 2414-98-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance decomposes
- Justification for type of information:
- other information are available
- Endpoint:
- partition coefficient
- Type of information:
- (Q)SAR
- Remarks:
- US EPA KOWWIN
- Adequacy of study:
- weight of evidence
- Study period:
- January 2021
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a (Q)SAR model, with limited documentation / justification, but validity of model and reliability of prediction considered adequate based on a generally acknowledged source
- Justification for type of information:
- The test item "Magnesium ethanolate" decomposes immediatly in contact with water. Therefore the partition coefficient was calculated by EPI Suite 4.11 (KOWWIN v. 1.68).
- Qualifier:
- according to guideline
- Guideline:
- other: Epi Suite Calculation
- Version / remarks:
- EPI Suite 4.11, KOWWIN v1.68
- Principles of method if other than guideline:
- Method: other, calculated with EPI Suite Version 4.11
KOWWIN (the Log Octanol-Water Partition Coefficient Program) estimates the logarithmic octanol-water partition coefficient (log P) of organic compounds. KOWWIN requires only a chemical structure to estimate a log P.
Structures are entered into KOWWIN by SMILES (Simplified Molecular Input Line Entry System) notations. Users unfamiliar with SMILES notations can consult the document "A Brief Description of SMILES Notation" (accessed by pressing the F1 key or selecting "Help" from the program menu). SMILES can be entered into KOWWIN by several methods. Structures in scientific file formats other than SMILES notations can be imported directly into KOWWIN
The KOWWIN program and estimation methodology were developed at Syracuse Research Corporation. A journal article by Meylan and Howard (1995) describes the program methodology.
- GLP compliance:
- no
- Type of method:
- other: calculation
- Remarks:
- EPI Suite Version 4.11
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- -1.01
- Temp.:
- 25 °C
- Remarks on result:
- other: QSAR
- Remarks:
- EPI Suite Version 4.11
- Conclusions:
- The calculated value of log Pow is -1.01 at 25°C. However, it is only a theoretical value, because the compound decomposes immediately upon contact with water (see also 5.1.2 Hydrolysis)..
Referenceopen allclose all
Description of key information
In the presence of water, magnesium ethanolate decomposes very rapidly by hydrolysis and ethanol and magnesium hydroxide are formed. See also IUCLID chapter 5.1.2 "Hydrolysis". Hydrolysis rates of >= 99% within 1 minute reaction time are observed. As such, in accordance with REACH Annex XI, 2., the study (required in Annex VII section 7.8) does not need to be conducted, because magnesium ethanolate cannot be dissolved in water or octanol without a chemical reaction happening. However, according to REACH Annex VII section 7.8, logKow of magnesium ethanolate was predicted by QSAR according to EPI Suite 4.11 (KOWWIN v. 1.68). The predicted LogKow is -1.01 at 25°C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.01
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.