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EC number: 208-863-7 | CAS number: 544-17-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Henry's Law constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- Henry's law constant
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Scientifically accepted method, but EPI Suite not validated for organic salts
- Principles of method if other than guideline:
- HENRY (v.3.10): Bond estimation method
- GLP compliance:
- no
- H:
- 0 Pa m³/mol
- Temp.:
- 25 °C
- Endpoint:
- Henry's law constant
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Scientifically acceptable publication
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Henry´s Law Constant was determined by measuring equilibrium partial pressures (dynamic method according to Scarano et al., 1971) for a series of known aqueous molalities.
- H:
- 0.019 Pa m³/mol
- Temp.:
- 25 °C
- Conclusions:
- The Henry's Law constant of formic acid was determined to be 0.019 Pa m³/mol at 25 °C.
- Executive summary:
The Henry´s Law constant of formic acid was determined by measuring equilibrium partial pressures (dynamic method according to Scarano et al., 1971) for a series of known aqueous molalities, resulting in a value 0.019 Pa m³/mol at 25°C (Khan & Brimblecomb, 1992).
- Endpoint:
- Henry's law constant
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Scientifically acceptable publication
- Justification for type of information:
- It is considered appropriate to address the Henry’s Law constant data requirement for calcium formate by read-across to an available study on formic acid.
Calcium formate is the calcium salt of formic acid, and will dissociate immediately in aqueous and biological surroundings to the formate ion. It is therefore expected that the environmental profile of formic acid and calcium formate will be similar. - Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Henry´s Law Constant was determined by measuring equilibrium partial pressures (dynamic method according to Scarano et al., 1971) for a series of known aqueous molalities.
- Specific details on test material used for the study:
- Formic acid is being used as a read-across for calcium formate.
- H:
- 0.019 Pa m³/mol
- Temp.:
- 25 °C
- Conclusions:
- The Henry's Law constant of formic acid was determined to be 0.019 Pa m³/mol at 25°C, and is considered suitable for read-across to calcium formate.
- Executive summary:
It is considered appropriate to address the Henry's Law constant data requirement for calcium formate by read-across to an available study on formic acid. Calcium formate is the calcium salt of formic acid, and will dissociate immediately in aqueous and biological surroundings to the formate ion. It is therefore expected that the environmental profile of formic acid and calcium formate will be similar.
The Henry´s Law constant of formic acid was determined by measuring equilibrium partial pressures (dynamic method according to Scarano et al., 1971) for a series of known aqueous molalities, resulting in a value 0.019 Pa m³/mol at 25°C (Khan & Brimblecomb, 1992). This value is therefore also considered for calcium formate.
Referenceopen allclose all
Henry's Law Constant (HLC) at 25 °C calculated
from vapor pressure (VP) and water solubility (Sol) using EPI values:
HLC = 0.444E-3 Pa*m³/mol
VP = 3.41 Pa
Sol = 1.0E+06 mg/L
Calcium formate is a solid compound with negligible vapor pressure. However, in solution it is in equilibrium with formic acid and volatilization from water is therefore pH dependent.
Description of key information
The Henry’s Law Constant (HLC) value for calcium formate has been addressed via read-across from an available study on formic acid, given that calcium formate is the calcium salt of formic acid, and will dissociate immediately in aqueous and biological surroundings to the formate ion. It is therefore expected that the environmental profile of formic acid and calcium formate will be similar.
The Henry´s Law constant of formic acid was determined by measuring equilibrium partial pressures (dynamic method according to Scarano et al., 1971) for a series of known aqueous molalities, resulting in a value 0.019 Pa m³/mol at 25°C (Khan & Brimblecomb, 1992). This value is therefore also considered for calcium formate.
From the water surface, the substance will not evaporate into the atmosphere.
Key value for chemical safety assessment
- Henry's law constant (H) (in Pa m³/mol):
- 0.019
- at the temperature of:
- 25 °C
Additional information
A read across was performed to formic acid in order to have a reliable value for the calculation of PNECsed and PNEC soil via the equilibrium partitioning method. The Henry's Law Constant (HLC) of formic acid was determined to be 0.019 Pa m³/mol at 25 °C (Khan & Brimblecomb, 1992).
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