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Diss Factsheets
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EC number: 204-635-6 | CAS number: 123-56-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Two aquatic studies are available covering two trophic levels:
Aquatic invertebrate (Aschacher 2002):
In a test conducted according to ÖNORM EN ISO 6314, Daphnia magna were exposed to succinimide to concentrations of 10, 11, 12, 13, 14, and 15 g succinimide/L (nominal values) for 24 h. The effects caused by these concentrations did not follow a dose response and an EC50 could not be identified in the test. The range finder showed that no immobilisation occurred when D. magna were exposed up to 5 g/L. Therefore, it is concluded that the 24-h EC50 (D. magna, immobilisation) is above 5 g/L and below 10 g/L.
Aquatic algae (Seeland-Fremer 2019):
In a growth inhibition study conducted according to OECD guideline 201 and GLP the freshwater algae Pseudokirchneriella subcapitata was exposed to 962, 293, 83.7, 25.8 and 6.18 mg succinimide/L (geometric mean of measured concentration) for 72 h. No significant effect was seen for the endpoint growth rate up to the highest concentration tested. The endpoint yield revealed a significant effect at 962 mg/L with 11 % inhibition.
72-h NOErC ≥ 960 mg test item/L
72-h LOErC > 960 mg test item/L
72-h NOEyC = 293 mg test item/L
72-h LOEyC = 960 mg test item/L
In an inherent biodegradability test according to EN ISO 9888 (Schoisswohl 2001) the test item degraded to 99 % within 4 days. Hence, the substance is considered to be inherently biodegradable.
Taking into account these results, the substance does not have to be classified as aquatic toxic according to the CLP Regulation (Regulation (EC) No 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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