Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

Notes:

Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry.

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Showing 191 results.

Name	EC no.	CAS no.	Date of inclusion	Intrinsic property(ies) referred to in Article 57	Decision
Benzene-1,2,4-tricarboxylic acid 1,2 anhydride trimellitic anhydride; TMA	209-008-0	552-30-7	27/06/2018	Respiratory sensitising properties (Article 57(f) - human health)	ED/61/2018 EU/2018/594	Details
Benzo[ghi]perylene	205-883-8	191-24-2	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED 61/2018	Details
Decamethylcyclopentasiloxane D5	208-764-9	541-02-6	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED 61/2018	Details
Dicyclohexyl phthalate DCHP	201-545-9	84-61-7	27/06/2018	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - human health)	EU/2018/636 ED/61/2018	Details
Disodium octaborate	234-541-0	12008-41-2	27/06/2018	Toxic for reproduction (Article 57c)	ED 61/2018	Details
Dodecamethylcyclohexasiloxane D6	208-762-8	540-97-6	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED 61/2018	Details
Ethylenediamine EDA	203-468-6	107-15-3	27/06/2018	Respiratory sensitising properties (Article 57(f) - human health)	ED 61/2018	Details
Lead	231-100-4	7439-92-1	27/06/2018	Toxic for reproduction (Article 57c)	ED 61/2018	Details
Octamethylcyclotetrasiloxane D4	209-136-7	556-67-2	27/06/2018	PBT (Article 57d) vPvB (Article 57e)	ED 61/2018	Details
Terphenyl, hydrogenated	262-967-7	61788-32-7	27/06/2018	vPvB (Article 57e)	ED 61/2018	Details
1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene (“Dechlorane Plus”™) covering any of its individual anti- and syn-isomers or any combination thereof	-	-	15/01/2018	vPvB (Article 57e)	ED 01/2018	Details
Benz[a]anthracene	200-280-6	56-55-3, 1718-53-2	15/01/2018	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED 01/2018	Details
Cadmium carbonate	208-168-9	513-78-0	15/01/2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED 01/2018	Details
Cadmium hydroxide	244-168-5	21041-95-2	15/01/2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED 01/2018	Details
Cadmium nitrate	233-710-6	10022-68-1, 10325-94-7	15/01/2018	Carcinogenic (Article 57a) Mutagenic (Article 57b) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED 01/2018	Details
Chrysene	205-923-4	218-01-9, 1719-03-5	15/01/2018	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED 01/2018	Details
Reaction products of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and 4-heptylphenol, branched and linear (RP-HP) with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl)	-	-	15/01/2018	Endocrine disrupting properties (Article 57(f) - environment)	ED 01/2018	Details
Perfluorohexane-1-sulphonic acid and its salts PFHxS	-	-	07/07/2017	vPvB (Article 57e)	ED/30/2017	Details
4,4'-isopropylidenediphenol Bisphenol A; BPA	201-245-8	80-05-7	12/01/2017	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health)	ED/30/2017 ED/01/2017 ED 01/2018	Details
4-heptylphenol, branched and linear substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof	-	-	12/01/2017	Endocrine disrupting properties (Article 57(f) - environment)	ED/01/2017	Details
Nonadecafluorodecanoic acid (PFDA) and its sodium and ammonium salts show/hide Decanoic acid, nonadecafluoro-, sodium salt EC no.: - \| CAS no.: 3830-45-3 Ammonium nonadecafluorodecanoate EC no.: 221-470-5 \| CAS no.: 3108-42-7 Nonadecafluorodecanoic acid EC no.: 206-400-3 \| CAS no.: 335-76-2	-	-	12/01/2017	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/01/2017	Details
p-(1,1-dimethylpropyl)phenol	201-280-9	80-46-6	12/01/2017	Endocrine disrupting properties (Article 57(f) - environment)	ED/01/2017	Details
Benzo[def]chrysene (Benzo[a]pyrene)	200-028-5	50-32-8	20/06/2016	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) PBT (Article 57d) vPvB (Article 57e)	ED/21/2016	Details
1,3-propanesultone	214-317-9	1120-71-4	17/12/2015	Carcinogenic (Article 57a)	ED/79/2015	Details
2,4-di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol (UV-327)	223-383-8	3864-99-1	17/12/2015	vPvB (Article 57e)	ED/79/2015	Details
2-(2H-benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol (UV-350)	253-037-1	36437-37-3	17/12/2015	vPvB (Article 57e)	ED/79/2015	Details
Nitrobenzene	202-716-0	98-95-3	17/12/2015	Toxic for reproduction (Article 57c)	ED/79/2015	Details
Perfluorononan-1-oic-acid and its sodium and ammonium salts show/hide Ammonium salts of perfluorononan-1-oic-acid EC no.: - \| CAS no.: -, 4149-60-4 Perfluorononan-1-oic-acid EC no.: 206-801-3 \| CAS no.: 375-95-1 Sodium salts of perfluorononan-1-oic-acid EC no.: - \| CAS no.: -, 21049-39-8	-	-	17/12/2015	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/79/2015	Details
1,2-benzenedicarboxylic acid, di-C6-10-alkyl esters or mixed decyl and hexyl and octyl diesters with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5) show/hide 1,2-Benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters EC no.: 272-013-1 \| CAS no.: 68648-93-1 1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters EC no.: 271-094-0 \| CAS no.: 68515-51-5	-	-	15/06/2015	Toxic for reproduction (Article 57c)	ED_39_2015.pdf	Details
5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [1], 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [2] covering any of the individual stereoisomers of [1] and [2] or any combination thereof show/hide 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC no.: - \| CAS no.: - 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC no.: - \| CAS no.: -	-	-	15/06/2015	vPvB (Article 57e)	ED/39/2015	Details
2-(2H-benzotriazol-2-yl)-4,6-ditertpentylphenol (UV-328)	247-384-8	25973-55-1	17/12/2014	PBT (Article 57d) vPvB (Article 57e)	ED/108/2014	Details
2-benzotriazol-2-yl-4,6-di-tert-butylphenol (UV-320)	223-346-6	3846-71-7	17/12/2014	PBT (Article 57d) vPvB (Article 57e)	ED/108/2014	Details
2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (DOTE)	239-622-4	15571-58-1	17/12/2014	Toxic for reproduction (Article 57c)	ED/108/2014	Details
Cadmium fluoride	232-222-0	7790-79-6	17/12/2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/108/2014	Details
Cadmium sulphate	233-331-6	10124-36-4, 31119-53-6	17/12/2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/108/2014	Details
Reaction mass of 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate and 2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (reaction mass of DOTE and MOTE)	-	-	17/12/2014	Toxic for reproduction (Article 57c)	ED/108/2014	Details
1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear	271-093-5	68515-50-4	16/06/2014	Toxic for reproduction (Article 57c)	ED/49/2014	Details
Cadmium chloride	233-296-7	10108-64-2	16/06/2014	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/49/2014	Details
Sodium perborate, perboric acid, sodium salt show/hide Perboric acid, sodium salt EC no.: 234-390-0 \| CAS no.: 11138-47-9 Sodium perborate EC no.: 239-172-9 \| CAS no.: 15120-21-5	-	-	16/06/2014	Toxic for reproduction (Article 57c)	ED/49/2014	Details
Sodium peroxometaborate	231-556-4	7632-04-4	16/06/2014	Toxic for reproduction (Article 57c)	ED/49/2014	Details
Cadmium sulphide	215-147-8	1306-23-6	16/12/2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/121/2013	Details
Dihexyl phthalate	201-559-5	84-75-3	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013	Details
Disodium 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalene-1-sulphonate) (C.I. Direct Red 28)	209-358-4	573-58-0	16/12/2013	Carcinogenic (Article 57a)	ED/121/2013	Details
Disodium 4-amino-3-[[4'-[(2,4-diaminophenyl)azo][1,1'-biphenyl]-4-yl]azo] -5-hydroxy-6-(phenylazo)naphthalene-2,7-disulphonate (C.I. Direct Black 38)	217-710-3	1937-37-7	16/12/2013	Carcinogenic (Article 57a)	ED/121/2013	Details
Imidazolidine-2-thione (2-imidazoline-2-thiol)	202-506-9	96-45-7	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013	Details
Lead di(acetate)	206-104-4	301-04-2	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013	Details
Trixylyl phosphate	246-677-8	25155-23-1	16/12/2013	Toxic for reproduction (Article 57c)	ED/121/2013	Details
4-Nonylphenol, branched and linear, ethoxylated substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof	-	-	20/06/2013	Endocrine disrupting properties (Article 57(f) - environment)	ED/69/2013	Details
Ammonium pentadecafluorooctanoate (APFO)	223-320-4	3825-26-1	20/06/2013	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/69/2013	Details
Cadmium	231-152-8	7440-43-9	20/06/2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/69/2013	Details
Cadmium oxide	215-146-2	1306-19-0	20/06/2013	Carcinogenic (Article 57a) Specific target organ toxicity after repeated exposure (Article 57(f) - human health)	ED/69/2013	Details
Dipentyl phthalate (DPP)	205-017-9	131-18-0	20/06/2013	Toxic for reproduction (Article 57c)	ED/69/2013	Details
Pentadecafluorooctanoic acid (PFOA)	206-397-9	335-67-1	20/06/2013	Toxic for reproduction (Article 57c) PBT (Article 57d)	ED/69/2013	Details
1,2-Benzenedicarboxylic acid, dipentyl ester, branched and linear	284-032-2	84777-06-0	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
1,2-diethoxyethane	211-076-1	629-14-1	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
1-bromopropane (n-propyl bromide)	203-445-0	106-94-5	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
3-ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine	421-150-7	143860-04-2	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
4,4'-methylenedi-o-toluidine	212-658-8	838-88-0	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
4,4'-oxydianiline and its salts show/hide 4,4'-oxydianiline EC no.: 202-977-0 \| CAS no.: 101-80-4	-	-	19/12/2012	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/169/2012	Details
4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated covering well-defined substances and UVCB substances, polymers and homologues	-	-	19/12/2012	Endocrine disrupting properties (Article 57(f) - environment)	ED/169/2012	Details
4-aminoazobenzene	200-453-6	60-09-3	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
4-methyl-m-phenylenediamine (toluene-2,4-diamine)	202-453-1	95-80-7	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
4-Nonylphenol, branched and linear substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof	-	-	19/12/2012	Endocrine disrupting properties (Article 57(f) - environment)	ED/169/2012	Details
6-methoxy-m-toluidine (p-cresidine)	204-419-1	120-71-8	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
[Phthalato(2-)]dioxotrilead	273-688-5	69011-06-9	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Acetic acid, lead salt, basic	257-175-3	51404-69-4	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Biphenyl-4-ylamine	202-177-1	92-67-1	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
Bis(pentabromophenyl) ether (decabromodiphenyl ether) (DecaBDE)	214-604-9	1163-19-5	19/12/2012	PBT (Article 57d) vPvB (Article 57e)	ED/169/2012	Details
Cyclohexane-1,2-dicarboxylic anhydride all possible combinations of the cis- and trans-isomers show/hide cis-cyclohexane-1,2-dicarboxylic anhydride EC no.: 236-086-3 \| CAS no.: 13149-00-3 Cyclohexane-1,2-dicarboxylic anhydride EC no.: 201-604-9 \| CAS no.: 85-42-7 trans-cyclohexane-1,2-dicarboxylic anhydride EC no.: 238-009-9 \| CAS no.: 14166-21-3	-	-	19/12/2012	Respiratory sensitising properties (Article 57(f) - human health)	ED/169/2012	Details
Diazene-1,2-dicarboxamide (C,C'-azodi(formamide)) (ADCA)	204-650-8	123-77-3	19/12/2012	Respiratory sensitising properties (Article 57(f) - human health)	ED/169/2012	Details
Dibutyltin dichloride (DBTC)	211-670-0	683-18-1	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Diethyl sulphate	200-589-6	64-67-5	19/12/2012	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/169/2012	Details
Diisopentyl phthalate	210-088-4	605-50-5	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Dimethyl sulphate	201-058-1	77-78-1	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
Dinoseb (6-sec-butyl-2,4-dinitrophenol)	201-861-7	88-85-7	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Dioxobis(stearato)trilead	235-702-8	12578-12-0	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Fatty acids, C16-18, lead salts	292-966-7	91031-62-8	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Furan	203-727-3	110-00-9	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
Henicosafluoroundecanoic acid	218-165-4	2058-94-8	19/12/2012	vPvB (Article 57e)	ED/169/2012	Details
Heptacosafluorotetradecanoic acid	206-803-4	376-06-7	19/12/2012	vPvB (Article 57e)	ED/169/2012	Details
Hexahydromethylphthalic anhydride including cis- and trans- stereo isomeric forms and all possible combinations of the isomers show/hide Hexahydro-4-methylphthalic anhydride EC no.: 243-072-0 \| CAS no.: 19438-60-9 Hexahydro-3-methylphthalic anhydride EC no.: 260-566-1 \| CAS no.: 57110-29-9 Hexahydro-1-methylphthalic anhydride EC no.: 256-356-4 \| CAS no.: 48122-14-1 Hexahydromethylphthalic anhydride EC no.: 247-094-1 \| CAS no.: 25550-51-0	-	-	19/12/2012	Respiratory sensitising properties (Article 57(f) - human health)	ED/169/2012	Details
Lead bis(tetrafluoroborate)	237-486-0	13814-96-5	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Lead cyanamidate	244-073-9	20837-86-9	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Lead dinitrate	233-245-9	10099-74-8	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Lead monoxide (lead oxide)	215-267-0	1317-36-8	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Lead oxide sulfate	234-853-7	12036-76-9	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Lead titanium trioxide	235-038-9	12060-00-3	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Lead titanium zirconium oxide	235-727-4	12626-81-2	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Methoxyacetic acid	210-894-6	625-45-6	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Methyloxirane (Propylene oxide)	200-879-2	75-56-9	19/12/2012	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/169/2012	Details
N,N-dimethylformamide	200-679-5	68-12-2	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
N-methylacetamide	201-182-6	79-16-3	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
N-pentyl-isopentylphthalate	-	776297-69-9	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
o-aminoazotoluene	202-591-2	97-56-3	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
o-toluidine	202-429-0	95-53-4	19/12/2012	Carcinogenic (Article 57a)	ED/169/2012	Details
Orange lead (lead tetroxide)	215-235-6	1314-41-6	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Pentacosafluorotridecanoic acid	276-745-2	72629-94-8	19/12/2012	vPvB (Article 57e)	ED/169/2012	Details
Pentalead tetraoxide sulphate	235-067-7	12065-90-6	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Pyrochlore, antimony lead yellow -	232-382-1	8012-00-8	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Silicic acid (H2Si2O5), barium salt (1:1), lead-doped with lead (Pb) content above the applicable generic concentration limit for ’toxicity for reproduction’ Repr. 1A (CLP) or category 1 (DSD),the substance is a member of the group entry of lead compounds, with index number 082-001-00-6 in Regulation (EC) No 1272/2008	272-271-5	68784-75-8	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Silicic acid, lead salt	234-363-3	11120-22-2	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Sulfurous acid, lead salt, dibasic	263-467-1	62229-08-7	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Tetraethyllead	201-075-4	78-00-2	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Tetralead trioxide sulphate	235-380-9	12202-17-4	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Tricosafluorododecanoic acid	206-203-2	307-55-1	19/12/2012	vPvB (Article 57e)	ED/169/2012	Details
Trilead bis(carbonate) dihydroxide	215-290-6	1319-46-6	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
Trilead dioxide phosphonate	235-252-2	12141-20-7	19/12/2012	Toxic for reproduction (Article 57c)	ED/169/2012	Details
1,2-bis(2-methoxyethoxy)ethane (TEGDME,triglyme)	203-977-3	112-49-2	18/06/2012	Toxic for reproduction (Article 57c)	ED/87/2012	Details
1,2-dimethoxyethane,ethylene glycol dimethyl ether (EGDME)	203-794-9	110-71-4	18/06/2012	Toxic for reproduction (Article 57c)	ED/87/2012	Details
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC)	219-514-3	2451-62-9	18/06/2012	Mutagenic (Article 57b)	ED/87/2012	Details
1,3,5-tris[(2S and 2R)-2,3-epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione (β-TGIC) -	423-400-0	59653-74-6	18/06/2012	Mutagenic (Article 57b)	ED/87/2012	Details
4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	209-218-2	561-41-1	18/06/2012	Carcinogenic (Article 57a)	ED/87/2012	Details
4,4'-bis(dimethylamino)benzophenone (Michler’s ketone)	202-027-5	90-94-8	18/06/2012	Carcinogenic (Article 57a)	ED/87/2012	Details
[4-[4,4'-bis(dimethylamino) benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium chloride (C.I. Basic Violet 3) with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	208-953-6	548-62-9	18/06/2012	Carcinogenic (Article 57a)	ED/87/2012	Details
[4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene] dimethylammonium chloride (C.I. Basic Blue 26) with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	219-943-6	2580-56-5	18/06/2012	Carcinogenic (Article 57a)	ED/87/2012	Details
Diboron trioxide	215-125-8	1303-86-2	18/06/2012	Toxic for reproduction (Article 57c)	ED/87/2012	Details
Formamide	200-842-0	75-12-7	18/06/2012	Toxic for reproduction (Article 57c)	ED/87/2012	Details
Lead(II) bis(methanesulfonate) -	401-750-5	17570-76-2	18/06/2012	Toxic for reproduction (Article 57c)	ED/87/2012	Details
N,N,N',N'-tetramethyl-4,4'-methylenedianiline (Michler’s base)	202-959-2	101-61-1	18/06/2012	Carcinogenic (Article 57a)	ED/87/2012	Details
α,α-Bis[4-(dimethylamino)phenyl]-4 (phenylamino)naphthalene-1-methanol (C.I. Solvent Blue 4) with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)	229-851-8	6786-83-0	18/06/2012	Carcinogenic (Article 57a)	ED/87/2012	Details
1,2-dichloroethane	203-458-1	107-06-2	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
2,2'-dichloro-4,4'-methylenedianiline	202-918-9	101-14-4	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
2-Methoxyaniline, o-Anisidine	201-963-1	90-04-0	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
4-(1,1,3,3-tetramethylbutyl)phenol	205-426-2	140-66-9	19/12/2011	Endocrine disrupting properties (Article 57(f) - environment)	ED/77/2011	Details
Aluminosilicate Refractory Ceramic Fibres are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium and silicon are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm) c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight	-	-	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011 ED/95/2012	Details
Arsenic acid	231-901-9	7778-39-4	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Bis(2-methoxyethyl) ether	203-924-4	111-96-6	19/12/2011	Toxic for reproduction (Article 57c)	ED/77/2011	Details
Bis(2-methoxyethyl) phthalate	204-212-6	117-82-8	19/12/2011	Toxic for reproduction (Article 57c)	ED/77/2011	Details
Calcium arsenate	231-904-5	7778-44-1	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Dichromium tris(chromate)	246-356-2	24613-89-6	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Formaldehyde, oligomeric reaction products with aniline	500-036-1	25214-70-4	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Lead diazide, Lead azide	236-542-1	13424-46-9	19/12/2011	Toxic for reproduction (Article 57c)	ED/77/2011	Details
Lead dipicrate	229-335-2	6477-64-1	19/12/2011	Toxic for reproduction (Article 57c)	ED/77/2011	Details
Lead styphnate	239-290-0	15245-44-0	19/12/2011	Toxic for reproduction (Article 57c)	ED/77/2011	Details
N,N-dimethylacetamide	204-826-4	127-19-5	19/12/2011	Toxic for reproduction (Article 57c)	ED/77/2011	Details
Pentazinc chromate octahydroxide	256-418-0	49663-84-5	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Phenolphthalein	201-004-7	77-09-8	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Potassium hydroxyoctaoxodizincatedichromate	234-329-8	11103-86-9	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011	Details
Trilead diarsenate	222-979-5	3687-31-8	19/12/2011	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/77/2011	Details
Zirconia Aluminosilicate Refractory Ceramic Fibres are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium, silicon and zirconium are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm). c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight	-	-	19/12/2011	Carcinogenic (Article 57a)	ED/77/2011 ED/95/2012	Details
1,2,3-trichloropropane	202-486-1	96-18-4	20/06/2011	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/31/2011	Details
1,2-Benzenedicarboxylic acid, di-C6-8-branched alkyl esters, C7-rich	276-158-1	71888-89-6	20/06/2011	Toxic for reproduction (Article 57c)	ED/31/2011	Details
1,2-Benzenedicarboxylic acid, di-C7-11-branched and linear alkyl esters	271-084-6	68515-42-4	20/06/2011	Toxic for reproduction (Article 57c)	ED/31/2011	Details
1-Methyl-2-pyrrolidone (NMP)	212-828-1	872-50-4	20/06/2011	Toxic for reproduction (Article 57c)	ED/31/2011	Details
2-ethoxyethyl acetate	203-839-2	111-15-9	20/06/2011	Toxic for reproduction (Article 57c)	ED/31/2011	Details
Hydrazine	206-114-9	302-01-2, 7803-57-8	20/06/2011	Carcinogenic (Article 57a)	ED/31/2011	Details
Strontium chromate	232-142-6	7789-06-2	20/06/2011	Carcinogenic (Article 57a)	ED/31/2011	Details
2-ethoxyethanol	203-804-1	110-80-5	15/12/2010	Toxic for reproduction (Article 57c)	ED/95/2010	Details
2-methoxyethanol	203-713-7	109-86-4	15/12/2010	Toxic for reproduction (Article 57c)	ED/95/2010	Details
Acids generated from chromium trioxide and their oligomers show/hide Dichromic acid EC no.: 236-881-5 \| CAS no.: 7738-94-5 Chromic acid EC no.: 231-801-5 \| CAS no.: 13530-68-2 Oligomers of chromic acid and dichromic acid EC no.: - \| CAS no.: -	-	-	15/12/2010	Carcinogenic (Article 57a)	ED/95/2010	Details
Chromium trioxide	215-607-8	1333-82-0	15/12/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/95/2010	Details
Cobalt(II) carbonate	208-169-4	513-79-1	15/12/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Cobalt(II) diacetate	200-755-8	71-48-7	15/12/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Cobalt(II) dinitrate	233-402-1	10141-05-6	15/12/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Cobalt(II) sulphate	233-334-2	10124-43-3	15/12/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/95/2010	Details
Ammonium dichromate	232-143-1	7789-09-5	18/06/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c)	ED/30/2010	Details
Boric acid EC No. 233-139-2 and EC No. 234-343-4 show/hide Boric acid, crude natural EC no.: 234-343-4 \| CAS no.: 11113-50-1 Boric acid EC no.: 233-139-2 \| CAS no.: 10043-35-3	-	-	18/06/2010	Toxic for reproduction (Article 57c)	ED/30/2010	Details
Disodium tetraborate, anhydrous	215-540-4	12179-04-3, 1303-96-4, 1330-43-4	18/06/2010	Toxic for reproduction (Article 57c)	ED/30/2010	Details
Potassium chromate	232-140-5	7789-00-6	18/06/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/30/2010	Details
Potassium dichromate	231-906-6	7778-50-9	18/06/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c)	ED/30/2010	Details
Sodium chromate	231-889-5	7775-11-3	18/06/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c)	ED/30/2010	Details
Tetraboron disodium heptaoxide, hydrate	235-541-3	12267-73-1	18/06/2010	Toxic for reproduction (Article 57c)	ED/30/2010	Details
Trichloroethylene	201-167-4	79-01-6	18/06/2010	Carcinogenic (Article 57a)	ED/30/2010	Details
Acrylamide	201-173-7	79-06-1	30/03/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b)	ED/68/2009	Details
2,4-dinitrotoluene	204-450-0	121-14-2	13/01/2010	Carcinogenic (Article 57a)	ED/68/2009	Details
Anthracene oil -	292-602-7	90640-80-5	13/01/2010	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene paste -	292-603-2	90640-81-6	13/01/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene paste, anthracene fraction -	295-275-9	91995-15-2	13/01/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene paste, distn. lights -	295-278-5	91995-17-4	13/01/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Anthracene oil, anthracene-low -	292-604-8	90640-82-7	13/01/2010	Carcinogenic (Article 57a) Mutagenic (Article 57b) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Diisobutyl phthalate	201-553-2	84-69-5	13/01/2010	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - human health)	EU/2017/4462 ED/30/2017 ED/68/2009	Details
Lead chromate	231-846-0	7758-97-6	13/01/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/68/2009	Details
Lead chromate molybdate sulphate red (C.I. Pigment Red 104) -	235-759-9	12656-85-8	13/01/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/68/2009	Details
Lead sulfochromate yellow (C.I. Pigment Yellow 34) -	215-693-7	1344-37-2	13/01/2010	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/68/2009	Details
Pitch, coal tar, high-temp. -	266-028-2	65996-93-2	13/01/2010	Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e)	ED/68/2009	Details
Tris(2-chloroethyl) phosphate	204-118-5	115-96-8	13/01/2010	Toxic for reproduction (Article 57c)	ED/68/2009	Details
4,4'- Diaminodiphenylmethane (MDA)	202-974-4	101-77-9	28/10/2008	Carcinogenic (Article 57a)	ED/67/2008	Details
5-tert-butyl-2,4,6-trinitro-m-xylene (Musk xylene)	201-329-4	81-15-2	28/10/2008	vPvB (Article 57e)	ED/67/2008	Details
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins)	287-476-5	85535-84-8	28/10/2008	PBT (Article 57d) vPvB (Article 57e)	ED/67/2008	Details
Anthracene	204-371-1	120-12-7	28/10/2008	PBT (Article 57d)	ED/67/2008	Details
Benzyl butyl phthalate (BBP)	201-622-7	85-68-7	28/10/2008	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - human health)	EU/2017/4462 ED/30/2017 ED/67/2008	Details
Bis (2-ethylhexyl)phthalate (DEHP)	204-211-0	117-81-7	28/10/2008	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health)	EU/2017/4462 ED/108/2014 ED/30/2017 ED/67/2008	Details
Bis(tributyltin) oxide (TBTO)	200-268-0	56-35-9	28/10/2008	PBT (Article 57d)	ED/67/2008	Details
Cobalt dichloride	231-589-4	7646-79-9	28/10/2008	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/31/2011 ED/67/2008	Details
Diarsenic pentaoxide	215-116-9	1303-28-2	28/10/2008	Carcinogenic (Article 57a)	ED/67/2008	Details
Diarsenic trioxide	215-481-4	1327-53-3	28/10/2008	Carcinogenic (Article 57a)	ED/67/2008	Details
Dibutyl phthalate (DBP)	201-557-4	84-74-2	28/10/2008	Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - human health)	EU/2017/4462 ED/30/2017 ED/67/2008	Details
Hexabromocyclododecane (HBCDD) and all major diastereoisomers identified show/hide Hexabromocyclododecane EC no.: 247-148-4 \| CAS no.: 25637-99-4 gamma-hexabromocyclododecane EC no.: - \| CAS no.: 134237-52-8 1,2,5,6,9,10-hexabromocyclodecane EC no.: 221-695-9 \| CAS no.: 3194-55-6 alpha-hexabromocyclododecane EC no.: - \| CAS no.: 134237-50-6 beta-hexabromocyclododecane EC no.: - \| CAS no.: 134237-51-7	-	-	28/10/2008	PBT (Article 57d)	ED/67/2008	Details
Lead hydrogen arsenate	232-064-2	7784-40-9	28/10/2008	Carcinogenic (Article 57a) Toxic for reproduction (Article 57c)	ED/67/2008	Details
Sodium dichromate	234-190-3	10588-01-9, 7789-12-0	28/10/2008	Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c)	ED/67/2008	Details
Triethyl arsenate -	427-700-2	15606-95-8	28/10/2008	Carcinogenic (Article 57a)	ED/67/2008	Details

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Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

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