Candidate List of substances of very high concern for Authorisation

Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

Notes:

  • Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
  • Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
  • Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry. 
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Decision IUCLID dataset  
215-116-9
1303-28-2
28-Oct-2008
Carcinogenic (Article 57a)
Details
215-481-4
1327-53-3
28-Oct-2008
Carcinogenic (Article 57a)
Details
246-356-2
24613-89-6
19-Dec-2011
Carcinogenic (Article 57a)
Details
200-589-6
64-67-5
19-Dec-2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
201-058-1
77-78-1
19-Dec-2012
Carcinogenic (Article 57a)
Details
209-358-4
573-58-0
16-Dec-2013
Carcinogenic (Article 57a)
Details
217-710-3
1937-37-7
16-Dec-2013
Carcinogenic (Article 57a)
Details
500-036-1
25214-70-4
19-Dec-2011
Carcinogenic (Article 57a)
Details
203-727-3
110-00-9
19-Dec-2012
Carcinogenic (Article 57a)
Details
206-114-9
302-01-2, 7803-57-8
20-Jun-2011
Carcinogenic (Article 57a)
Details
231-846-0
7758-97-6
13-Jan-2010
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
-
235-759-9
12656-85-8
13-Jan-2010
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
232-064-2
7784-40-9
28-Oct-2008
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
-
215-693-7
1344-37-2
13-Jan-2010
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
200-879-2
75-56-9
19-Dec-2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
202-959-2
101-61-1
18-Jun-2012
Carcinogenic (Article 57a)
Details
213-103-2
924-42-5
10-Jun-2022
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
202-591-2
97-56-3
19-Dec-2012
Carcinogenic (Article 57a)
Details
202-429-0
95-53-4
19-Dec-2012
Carcinogenic (Article 57a)
Details
256-418-0
49663-84-5
19-Dec-2011
Carcinogenic (Article 57a)
Details
201-004-7
77-09-8
19-Dec-2011
Carcinogenic (Article 57a)
Details
-
266-028-2
65996-93-2
13-Jan-2010
Carcinogenic (Article 57a)
PBT (Article 57d)
vPvB (Article 57e)
Details
232-140-5
7789-00-6
18-Jun-2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Details
231-906-6
7778-50-9
18-Jun-2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Toxic for reproduction (Article 57c)
Details
234-329-8
11103-86-9
19-Dec-2011
Carcinogenic (Article 57a)
Details
231-889-5
7775-11-3
18-Jun-2010
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Toxic for reproduction (Article 57c)
Details
234-190-3
10588-01-9, 7789-12-0
28-Oct-2008
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
Toxic for reproduction (Article 57c)
Details
232-142-6
7789-06-2
20-Jun-2011
Carcinogenic (Article 57a)
Details
201-167-4
79-01-6
18-Jun-2010
Carcinogenic (Article 57a)
Details
-
427-700-2
15606-95-8
28-Oct-2008
Carcinogenic (Article 57a)
Details
222-979-5
3687-31-8
19-Dec-2011
Carcinogenic (Article 57a)
Toxic for reproduction (Article 57c)
Details
are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium, silicon and zirconium are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm). c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight
show/hide
Refractories, fibers, aluminosilicate EC No.: - | CAS No.: 142844-00-6
-
-
19-Dec-2011
Carcinogenic (Article 57a)
Details
with ≥ 0.1% of Michler's ketone (EC No. 202-027-5) or Michler's base (EC No. 202-959-2)
229-851-8
6786-83-0
18-Jun-2012
Carcinogenic (Article 57a)
Details
3-benzylidene camphor; 3-BC
239-139-9
15087-24-8
15-Jan-2019
Endocrine disrupting properties (Article 57(f) - environment)
Details
201-025-1
77-40-7
08-Jul-2021
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
Bisphenol A; BPA
201-245-8
80-05-7
12-Jan-2017
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
201-250-5
80-09-1
17-Jan-2023
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
205-426-2
140-66-9
19-Dec-2011
Endocrine disrupting properties (Article 57(f) - environment)
Details
covering well-defined substances and UVCB substances, polymers and homologues
-
-
19-Dec-2012
Endocrine disrupting properties (Article 57(f) - environment)
Details
substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
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Phenol, heptyl derivs. EC No.: 276-743-1 | CAS No.: 72624-02-3
4-heptylphenol EC No.: 217-862-0 | CAS No.: 1987-50-4
4-(2,3,3-trimethylbutan-2-yl)phenol EC No.: - | CAS No.: 72861-06-4
4-(2,4-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 33104-11-9
4-(3-ethylpentan-3-yl)phenol EC No.: - | CAS No.: 37872-24-5
4-(2-methylhexan-2-yl)phenol EC No.: - | CAS No.: 30784-31-7
4-(3,3-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 911371-06-7
4-(3-methylhexan-2-yl)phenol EC No.: - | CAS No.: 854904-93-1
4-(4,4-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 911371-07-8
4-(4-methylhexan-2-yl)phenol EC No.: - | CAS No.: 71945-81-8
4-(3-methylhexan-3-yl)phenol EC No.: - | CAS No.: 30784-32-8
4-(2,2-dimethylpentan-3-yl)phenol EC No.: - | CAS No.: 861010-65-3
4-(5-methylhexan-3-yl)phenol EC No.: - | CAS No.: 854904-92-0
4-(heptan-3-yl)phenol EC No.: - | CAS No.: 6465-74-3
4-(heptan-2-yl)phenol EC No.: - | CAS No.: 6863-24-7
4-(heptan-4-yl)phenol EC No.: - | CAS No.: 6465-71-0
4-(3-ethylpentyl)phenol EC No.: - | CAS No.: 911370-98-4
4-(3-methylhexyl)phenol EC No.: - | CAS No.: 102570-52-5
4-(4-methylhexyl)phenol EC No.: - | CAS No.: 1139800-98-8
4-(5-methylhexyl)phenol EC No.: - | CAS No.: 100532-36-3
4-(2,4-dimethylpentan-3-yl)phenol EC No.: - | CAS No.: 1824346-00-0
4-(2,3-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 861011-60-1
Phenol, 4-(1-ethyl-1,2-dimethylpropyl)- EC No.: - | CAS No.: 30784-27-1
Phenol, 4-tert-heptyl- EC No.: - | CAS No.: 288864-02-8
4-(5-methylhexan-2-yl)phenol EC No.: - | CAS No.: 857629-71-1
-
-
12-Jan-2017
Endocrine disrupting properties (Article 57(f) - environment)
Details
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
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p-isononylphenol EC No.: 247-770-6 | CAS No.: 26543-97-5
4-(1-Ethyl-1,4-dimethylpentyl)phenol EC No.: - | CAS No.: 142731-63-3
4-(1-Ethyl-1,3-dimethylpentyl)phenol EC No.: - | CAS No.: 186825-36-5
p-(1-methyloctyl)phenol EC No.: 241-427-4 | CAS No.: 17404-66-9
p-(1,1-dimethylheptyl)phenol EC No.: 250-339-5 | CAS No.: 30784-30-6
4-(1-ethyl-1-methylhexyl)phenol EC No.: 257-907-1 | CAS No.: 52427-13-1
p-nonylphenol EC No.: 203-199-4 | CAS No.: 104-40-5
Phenol, 4-nonyl-, branched EC No.: 284-325-5 | CAS No.: 84852-15-3
4-(3-ethylheptan-2-yl)phenol EC No.: - | CAS No.: 186825-39-8
4-(1,1,5-Trimethylhexyl)phenol EC No.: - | CAS No.: 521947-27-3
Isononylphenol EC No.: 234-284-4 | CAS No.: 11066-49-2
Phenol, nonyl-, branched EC No.: 291-844-0 | CAS No.: 90481-04-2
Nonylphenol EC No.: 246-672-0 | CAS No.: 25154-52-3
-
-
19-Dec-2012
Endocrine disrupting properties (Article 57(f) - environment)
Details
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, ethoxylated covering UVCB- and well-defined substances, polymers and homologues, which include any of the individual isomers and/or combinations thereof
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20-(4-nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 248-743-1 | CAS No.: 27942-27-4
2-[2-[2-[2-(4-nonylphenoxy)ethoxy]ethoxy]ethoxy]ethanol EC No.: 230-770-5 | CAS No.: 7311-27-5
Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
EC No.: 500-209-1 | CAS No.: 68412-54-4
4-Nonylphenol, ethoxylated
1 - 2.5 moles ethoxylated
EC No.: 500-045-0 | CAS No.: 26027-38-3
Nonylphenol, ethoxylated EC No.: 500-024-6 | CAS No.: 9016-45-9
Nonylphenol, ethoxylated (10-EO) EC No.: - | CAS No.: 9016-45-9
Nonylphenol, ethoxylated (8-EO) EC No.: - | CAS No.: 9016-45-9
Nonylphenol, ethoxylated (6,5-EO) EC No.: - | CAS No.: 9016-45-9
2-[2-(4-nonylphenoxy)ethoxy]ethanol EC No.: 243-816-4 | CAS No.: 20427-84-3
Nonylphenol, ethoxylated (15-EO) EC No.: - | CAS No.: 9016-45-9
14-(nonylphenoxy)-3,6,9,12-tetraoxatetradecan-1-ol EC No.: 247-555-7 | CAS No.: 26264-02-8
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol EC No.: 247-816-5 | CAS No.: 26571-11-9
2-[2-(nonylphenoxy)ethoxy]ethanol EC No.: 248-291-5 | CAS No.: 27176-93-8
20-(nonylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 248-292-0 | CAS No.: 27177-03-3
23-(nonylphenoxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol EC No.: 248-293-6 | CAS No.: 27177-05-5
29-(nonylphenoxy)-3,6,9,12,15,18,21,24,27-nonaoxanonacosanol EC No.: 248-294-1 | CAS No.: 27177-08-8
2-(nonylphenoxy)ethanol EC No.: 248-762-5 | CAS No.: 27986-36-3
26-(nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol; EC No.: 255-695-5 | CAS No.: 42173-90-0
2-(isononylphenoxy)ethanol EC No.: 284-987-5 | CAS No.: 85005-55-6
20-(isononylphenoxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 265-785-6 | CAS No.: 65455-69-8
4-Nonylphenol, branched, ethoxylated
1 - 2.5 moles ethoxylated
EC No.: 500-315-8 | CAS No.: 127087-87-0
4-Nonylphenol, branched, ethoxylated EC No.: - | CAS No.: 127087-87-0
Nonylphenol, ethoxylated (EO = 10) EC No.: - | CAS No.: -
Nonylphenol, ethoxylated (EO = 4) EC No.: - | CAS No.: -
Nonylphenol, ethoxylated (polymer) EC No.: - | CAS No.: -
2-[4-(3,6-dimethylheptan-3-yl)phenoxy]ethanol EC No.: - | CAS No.: 1119449-37-4
Nonylphenolpolyglycolether EC No.: - | CAS No.: -
Isononylphenol, ethoxylated EC No.: - | CAS No.: 37205-87-1
2-(4-nonylphenoxy)ethanol EC No.: - | CAS No.: 104-35-8
4-t-Nonylphenol-diethoxylate EC No.: - | CAS No.: 156609-10-8
-
-
20-Jun-2013
Endocrine disrupting properties (Article 57(f) - environment)
Details
202-679-0
98-54-4
16-Jul-2019
Endocrine disrupting properties (Article 57(f) - environment)
Details
204-211-0
117-81-7
28-Oct-2008
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
201-557-4
84-74-2
28-Oct-2008
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
201-280-9
80-46-6
12-Jan-2017
Endocrine disrupting properties (Article 57(f) - environment)
Details
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4-isododecylphenol EC No.: - | CAS No.: 27459-10-5
Phenol, tetrapropylene- EC No.: - | CAS No.: 57427-55-1
Phenol, 4-dodecyl, branched EC No.: - | CAS No.: 210555-94-5
Phenol, (tetrapropenyl) derivatives EC No.: - | CAS No.: 74499-35-7
Phenol, 4-isododecyl- EC No.: - | CAS No.: 27147-75-7
Phenol, dodecyl-, branched EC No.: 310-154-3 | CAS No.: 121158-58-5
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-
08-Jul-2021
Toxic for reproduction (Article 57c)
Endocrine disrupting properties (Article 57(f) - environment)
Endocrine disrupting properties (Article 57(f) - human health)
Details
with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl)
-
-
15-Jan-2018
Endocrine disrupting properties (Article 57(f) - environment)
Details
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tris(nonylphenyl) phosphite EC No.: 247-759-6 | CAS No.: 26523-78-4
Phenol, 4-nonyl-, phosphite (3:1) EC No.: - | CAS No.: 3050-88-2
Phenol, p-isononyl-, phosphite (3:1) EC No.: - | CAS No.: 31631-13-7
Phenol, p-sec-nonyl-, phosphite EC No.: - | CAS No.: 106599-06-8
-
-
16-Jul-2019
Endocrine disrupting properties (Article 57(f) - environment)
Details
-
-
17-Jan-2022
Endocrine disrupting properties (Article 57(f) - human health)
Details

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